Matches in SemOpenAlex for { <https://semopenalex.org/work/W2052287941> ?p ?o ?g. }
- W2052287941 endingPage "1529" @default.
- W2052287941 startingPage "1510" @default.
- W2052287941 abstract "The emergence of pandemic H1N1 influenza viruses in April 2009 and the continuous evolution of highly pathogenic H5N1 influenza viruses underscore the urgency of novel approaches to chemotherapy for human influenza infection. Anti-influenza drugs are currently limited to the neuraminidase inhibitors (oseltamivir and zanamivir) and to M2 ion channel blockers (amantadine and rimantadine), although resistance to the latter class develops rapidly. Potential targets for the development of new anti-influenza agents include the viral polymerase (and endonuclease), the hemagglutinin, and the non-structural protein NS1. The limitations of monotherapy and the emergence of drug-resistant variants make combination chemotherapy the logical therapeutic option. Here we review the experimental data on combination chemotherapy with currently available agents and the development of new agents and therapy targets." @default.
- W2052287941 created "2016-06-24" @default.
- W2052287941 creator A5067937189 @default.
- W2052287941 creator A5091454011 @default.
- W2052287941 date "2010-07-27" @default.
- W2052287941 modified "2023-10-06" @default.
- W2052287941 title "Combination Chemotherapy for Influenza" @default.
- W2052287941 cites W172556841 @default.
- W2052287941 cites W1893105611 @default.
- W2052287941 cites W1973199150 @default.
- W2052287941 cites W1984468567 @default.
- W2052287941 cites W1985003322 @default.
- W2052287941 cites W1988851601 @default.
- W2052287941 cites W1996311210 @default.
- W2052287941 cites W1999803849 @default.
- W2052287941 cites W2001676988 @default.
- W2052287941 cites W2001734810 @default.
- W2052287941 cites W2003926950 @default.
- W2052287941 cites W2004189247 @default.
- W2052287941 cites W2006934056 @default.
- W2052287941 cites W2009428685 @default.
- W2052287941 cites W2011434065 @default.
- W2052287941 cites W2014210710 @default.
- W2052287941 cites W2017594736 @default.
- W2052287941 cites W2020852349 @default.
- W2052287941 cites W2026515977 @default.
- W2052287941 cites W2029634452 @default.
- W2052287941 cites W2038565315 @default.
- W2052287941 cites W2043580251 @default.
- W2052287941 cites W2044088857 @default.
- W2052287941 cites W2047400336 @default.
- W2052287941 cites W2052187559 @default.
- W2052287941 cites W2067498763 @default.
- W2052287941 cites W2067819852 @default.
- W2052287941 cites W2074681797 @default.
- W2052287941 cites W2075881925 @default.
- W2052287941 cites W2079066605 @default.
- W2052287941 cites W2086358466 @default.
- W2052287941 cites W2102368840 @default.
- W2052287941 cites W2104873628 @default.
- W2052287941 cites W2105027884 @default.
- W2052287941 cites W2106915811 @default.
- W2052287941 cites W2107858461 @default.
- W2052287941 cites W2108367829 @default.
- W2052287941 cites W2110116923 @default.
- W2052287941 cites W2111910999 @default.
- W2052287941 cites W2112872044 @default.
- W2052287941 cites W2113038532 @default.
- W2052287941 cites W2117004115 @default.
- W2052287941 cites W2117235713 @default.
- W2052287941 cites W2118764399 @default.
- W2052287941 cites W2119394949 @default.
- W2052287941 cites W2122988122 @default.
- W2052287941 cites W2125902066 @default.
- W2052287941 cites W2126352919 @default.
- W2052287941 cites W2128924487 @default.
- W2052287941 cites W2129482297 @default.
- W2052287941 cites W2130679801 @default.
- W2052287941 cites W2138198678 @default.
- W2052287941 cites W2138274210 @default.
- W2052287941 cites W2144748415 @default.
- W2052287941 cites W2145825913 @default.
- W2052287941 cites W2149083438 @default.
- W2052287941 cites W2149251191 @default.
- W2052287941 cites W2152283024 @default.
- W2052287941 cites W2153207056 @default.
- W2052287941 cites W2162820439 @default.
- W2052287941 cites W2165260654 @default.
- W2052287941 cites W2168154559 @default.
- W2052287941 cites W2172229248 @default.
- W2052287941 cites W21890029 @default.
- W2052287941 cites W2270258930 @default.
- W2052287941 cites W233229719 @default.
- W2052287941 cites W2412876393 @default.
- W2052287941 cites W2468534749 @default.
- W2052287941 cites W2484676188 @default.
- W2052287941 cites W2508794604 @default.
- W2052287941 cites W4299387521 @default.
- W2052287941 cites W73431061 @default.
- W2052287941 doi "https://doi.org/10.3390/v2081510" @default.
- W2052287941 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3185732" @default.
- W2052287941 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21994692" @default.
- W2052287941 hasPublicationYear "2010" @default.
- W2052287941 type Work @default.
- W2052287941 sameAs 2052287941 @default.
- W2052287941 citedByCount "58" @default.
- W2052287941 countsByYear W20522879412012 @default.
- W2052287941 countsByYear W20522879412013 @default.
- W2052287941 countsByYear W20522879412014 @default.
- W2052287941 countsByYear W20522879412015 @default.
- W2052287941 countsByYear W20522879412016 @default.
- W2052287941 countsByYear W20522879412017 @default.
- W2052287941 countsByYear W20522879412018 @default.
- W2052287941 countsByYear W20522879412019 @default.
- W2052287941 countsByYear W20522879412020 @default.
- W2052287941 countsByYear W20522879412021 @default.
- W2052287941 countsByYear W20522879412022 @default.
- W2052287941 countsByYear W20522879412023 @default.