Matches in SemOpenAlex for { <https://semopenalex.org/work/W2052312989> ?p ?o ?g. }
- W2052312989 endingPage "1457" @default.
- W2052312989 startingPage "1449" @default.
- W2052312989 abstract "Different strategies have been explored for the purpose of autologous or allogeneic dermal regeneration. We have developed a hybrid matrix by lyophilizing collagen within a poly[(lactic acid)-co-(glycolic acid)] (10:90, molar composition) knitted mesh, in order to assimilate the advantages of natural and synthetic materials. The porosity of the mesh was found to be almost 95 %, using Micro-Computed Tomography Analysis, while the mechanical properties were comparable to native skin. In vitro biocompatibility was analyzed by culturing rat dermal fibroblasts in the matrices over 10 days. The cells were able to attach, proliferate and remain viable within the hybrid matrices. Subsequently, in vivo biocompatibility was analyzed by implanting the matrices subcutaneously in immunocompetent rats, for 2 weeks. Histological analysis showed that the poly[(lactic acid)-co-(glycolic acid)]–collagen hybrid matrices evoked minimal host tissue response in vivo. This study forms the basis of using poly[(lactic acid)-co-(glycolic acid)]–collagen hybrid matrices for our future work to develop a bioactive matrix for dermal regeneration. Copyright © 2005 Society of Chemical Industry" @default.
- W2052312989 created "2016-06-24" @default.
- W2052312989 creator A5003215109 @default.
- W2052312989 creator A5014693062 @default.
- W2052312989 creator A5019383491 @default.
- W2052312989 creator A5030098277 @default.
- W2052312989 creator A5048993461 @default.
- W2052312989 creator A5063703800 @default.
- W2052312989 creator A5083806034 @default.
- W2052312989 creator A5084214247 @default.
- W2052312989 date "2005-01-01" @default.
- W2052312989 modified "2023-09-25" @default.
- W2052312989 title "Characterization of a novel bioactive poly[(lactic acid)-co-(glycolic acid)] and collagen hybrid matrix for dermal regeneration" @default.
- W2052312989 cites W1970525947 @default.
- W2052312989 cites W1996507944 @default.
- W2052312989 cites W2006875835 @default.
- W2052312989 cites W2010201045 @default.
- W2052312989 cites W2032207006 @default.
- W2052312989 cites W2035064671 @default.
- W2052312989 cites W2038860414 @default.
- W2052312989 cites W2056163086 @default.
- W2052312989 cites W2074639428 @default.
- W2052312989 cites W2080312629 @default.
- W2052312989 cites W2085886780 @default.
- W2052312989 cites W2088856681 @default.
- W2052312989 cites W2089791526 @default.
- W2052312989 cites W2111281055 @default.
- W2052312989 cites W2118877693 @default.
- W2052312989 cites W2131082021 @default.
- W2052312989 cites W2132958134 @default.
- W2052312989 cites W23109058 @default.
- W2052312989 cites W2315942037 @default.
- W2052312989 cites W2910256229 @default.
- W2052312989 cites W4233068027 @default.
- W2052312989 cites W4246108954 @default.
- W2052312989 cites W4361804755 @default.
- W2052312989 doi "https://doi.org/10.1002/pi.1868" @default.
- W2052312989 hasPublicationYear "2005" @default.
- W2052312989 type Work @default.
- W2052312989 sameAs 2052312989 @default.
- W2052312989 citedByCount "6" @default.
- W2052312989 countsByYear W20523129892013 @default.
- W2052312989 countsByYear W20523129892014 @default.
- W2052312989 countsByYear W20523129892017 @default.
- W2052312989 crossrefType "journal-article" @default.
- W2052312989 hasAuthorship W2052312989A5003215109 @default.
- W2052312989 hasAuthorship W2052312989A5014693062 @default.
- W2052312989 hasAuthorship W2052312989A5019383491 @default.
- W2052312989 hasAuthorship W2052312989A5030098277 @default.
- W2052312989 hasAuthorship W2052312989A5048993461 @default.
- W2052312989 hasAuthorship W2052312989A5063703800 @default.
- W2052312989 hasAuthorship W2052312989A5083806034 @default.
- W2052312989 hasAuthorship W2052312989A5084214247 @default.
- W2052312989 hasConcept C105702510 @default.
- W2052312989 hasConcept C106487976 @default.
- W2052312989 hasConcept C127413603 @default.
- W2052312989 hasConcept C136229726 @default.
- W2052312989 hasConcept C150903083 @default.
- W2052312989 hasConcept C159985019 @default.
- W2052312989 hasConcept C171056886 @default.
- W2052312989 hasConcept C171250308 @default.
- W2052312989 hasConcept C178790620 @default.
- W2052312989 hasConcept C185592680 @default.
- W2052312989 hasConcept C192562407 @default.
- W2052312989 hasConcept C202751555 @default.
- W2052312989 hasConcept C207001950 @default.
- W2052312989 hasConcept C2775920511 @default.
- W2052312989 hasConcept C2777230088 @default.
- W2052312989 hasConcept C2777624698 @default.
- W2052312989 hasConcept C2778414984 @default.
- W2052312989 hasConcept C2780472526 @default.
- W2052312989 hasConcept C42360764 @default.
- W2052312989 hasConcept C49892992 @default.
- W2052312989 hasConcept C523546767 @default.
- W2052312989 hasConcept C54355233 @default.
- W2052312989 hasConcept C55493867 @default.
- W2052312989 hasConcept C71924100 @default.
- W2052312989 hasConcept C86803240 @default.
- W2052312989 hasConcept C95444343 @default.
- W2052312989 hasConceptScore W2052312989C105702510 @default.
- W2052312989 hasConceptScore W2052312989C106487976 @default.
- W2052312989 hasConceptScore W2052312989C127413603 @default.
- W2052312989 hasConceptScore W2052312989C136229726 @default.
- W2052312989 hasConceptScore W2052312989C150903083 @default.
- W2052312989 hasConceptScore W2052312989C159985019 @default.
- W2052312989 hasConceptScore W2052312989C171056886 @default.
- W2052312989 hasConceptScore W2052312989C171250308 @default.
- W2052312989 hasConceptScore W2052312989C178790620 @default.
- W2052312989 hasConceptScore W2052312989C185592680 @default.
- W2052312989 hasConceptScore W2052312989C192562407 @default.
- W2052312989 hasConceptScore W2052312989C202751555 @default.
- W2052312989 hasConceptScore W2052312989C207001950 @default.
- W2052312989 hasConceptScore W2052312989C2775920511 @default.
- W2052312989 hasConceptScore W2052312989C2777230088 @default.
- W2052312989 hasConceptScore W2052312989C2777624698 @default.
- W2052312989 hasConceptScore W2052312989C2778414984 @default.
- W2052312989 hasConceptScore W2052312989C2780472526 @default.
- W2052312989 hasConceptScore W2052312989C42360764 @default.