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- W2052349996 abstract "To improve the biocompatibility of polyurethane (PU) and bioprosthetic tissue (BT), they were chemically grafted with a hydrophilic poly(ethylene oxide) (PEO) and further negatively charged sulfonate groups (SO 3 ) to produce PU-PEO-SO 3 and BT-PEO-SO 3 , respectively. PU-PEO-SO 3 was much more blood compatible than untreated PU and PU-PEO, and the degree of surface cracking and calcification on implanted PUs was decreased in the following order: PU > PU-PEO > PU-PEO-SO 3 . Also, less calcium deposition of BT-PEO-SO 3 than that of BT control was observed in in vivo animal tests. Such superior blood compatibility, biostability, and anticalcification of sulfonated PEO-grafted PUs and tissues might be attributed to synergistic effects of nonadhesive and mobile PEO and negative sulfonate acid groups via a negative cilia model." @default.
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- W2052349996 date "1997-06-01" @default.
- W2052349996 modified "2023-09-27" @default.
- W2052349996 title "Negative cilia model for biocompatibility: Sulfonated peo-grafted polymers and tissues" @default.
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- W2052349996 doi "https://doi.org/10.1002/masy.19971180174" @default.
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