FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2052423003> ?p ?o ?g. }

• W2052423003 endingPage "225" @default.
• W2052423003 startingPage "219" @default.
• W2052423003 abstract "Many virus infections result in the suppression of one or more functions of the immune system. Multiple mechanisms have been proposed to explain viral-induced immunosuppression, including an imbalance in the cellular Th1/Th2 or cytokine profile, induction of anergy, depletion of effector cells and most recently the activation of CD4+CD25+ regulatory T (T reg) cells. CD4+CD25+ T reg cells are a subset of circulating CD4+ T cells with suppressive properties. CD4+CD25+ T reg cells were first identified in mice as cells capable of maintaining self-tolerance by suppressing autoreactive T cells. This review focuses on interactions between CD4+CD25+ T reg cells and viral pathogens. Most cases in which CD4+CD25+ T reg cells participate in response to infection reported so far involve chronic or persistent viral infections. Examples have been growing recently and include members of different viral families including retroviridae, herpesviridae and picornaviridae. It is currently not known how microbes are recognized by CD4+CD25+ T reg cells and whether exoantigen-specific T reg cells are of the same lineage as self-reacting natural T reg cells or represent peripherally induced counterparts derived from CD4+CD25- T cells. The findings that T reg cells influence the functional immunity during viral infections, however, might indicate that, in some cases, virus-specific T reg cells not only influence immune pathology or prevent pathogen elimination but also can promote a generalized state of immunosuppression in vivo such that the host is more susceptible to secondary infections with other pathogens or has reduced resistance to tumors. Conceivably, the activities of T reg cells might be one of the contributing reasons why it has been difficult so far to produce effective vaccines against some persisting viral infections." @default.
• W2052423003 created "2016-06-24" @default.
• W2052423003 creator A5036288870 @default.
• W2052423003 creator A5046324927 @default.
• W2052423003 creator A5076308485 @default.
• W2052423003 date "2005-10-01" @default.
• W2052423003 modified "2023-09-30" @default.
• W2052423003 title "The role of CD4+CD25+ regulatory T cells in viral infections" @default.
• W2052423003 cites W1530044612 @default.
• W2052423003 cites W1551777364 @default.
• W2052423003 cites W1555765668 @default.
• W2052423003 cites W1566416470 @default.
• W2052423003 cites W1578854334 @default.
• W2052423003 cites W1611284225 @default.
• W2052423003 cites W1615763679 @default.
• W2052423003 cites W1801247541 @default.
• W2052423003 cites W1801506204 @default.
• W2052423003 cites W1966288604 @default.
• W2052423003 cites W1970959631 @default.
• W2052423003 cites W1972308909 @default.
• W2052423003 cites W1989010737 @default.
• W2052423003 cites W1992997765 @default.
• W2052423003 cites W2002726823 @default.
• W2052423003 cites W2003276121 @default.
• W2052423003 cites W2004998289 @default.
• W2052423003 cites W2005227771 @default.
• W2052423003 cites W2008724419 @default.
• W2052423003 cites W2011659919 @default.
• W2052423003 cites W2025813544 @default.
• W2052423003 cites W2026208522 @default.
• W2052423003 cites W2026426963 @default.
• W2052423003 cites W2053642404 @default.
• W2052423003 cites W2054726751 @default.
• W2052423003 cites W2061805755 @default.
• W2052423003 cites W2063679726 @default.
• W2052423003 cites W2072494602 @default.
• W2052423003 cites W2084560238 @default.
• W2052423003 cites W2093608608 @default.
• W2052423003 cites W2095040060 @default.
• W2052423003 cites W2097811455 @default.
• W2052423003 cites W2104357791 @default.
• W2052423003 cites W2104374116 @default.
• W2052423003 cites W2108690268 @default.
• W2052423003 cites W2110753254 @default.
• W2052423003 cites W2113190700 @default.
• W2052423003 cites W2121681687 @default.
• W2052423003 cites W2127432084 @default.
• W2052423003 cites W2131633419 @default.
• W2052423003 cites W2132926599 @default.
• W2052423003 cites W2133052855 @default.
• W2052423003 cites W2135698322 @default.
• W2052423003 cites W2149123553 @default.
• W2052423003 cites W2156672979 @default.
• W2052423003 cites W2162792939 @default.
• W2052423003 cites W2162866571 @default.
• W2052423003 cites W2168545613 @default.
• W2052423003 cites W2171909981 @default.
• W2052423003 cites W2792966232 @default.
• W2052423003 cites W4313324526 @default.
• W2052423003 doi "https://doi.org/10.1016/j.vetimm.2005.07.011" @default.
• W2052423003 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16126280" @default.
• W2052423003 hasPublicationYear "2005" @default.
• W2052423003 type Work @default.
• W2052423003 sameAs 2052423003 @default.
• W2052423003 citedByCount "44" @default.
• W2052423003 countsByYear W20524230032012 @default.
• W2052423003 countsByYear W20524230032013 @default.
• W2052423003 countsByYear W20524230032014 @default.
• W2052423003 countsByYear W20524230032015 @default.
• W2052423003 countsByYear W20524230032016 @default.
• W2052423003 countsByYear W20524230032018 @default.
• W2052423003 countsByYear W20524230032020 @default.
• W2052423003 countsByYear W20524230032021 @default.
• W2052423003 countsByYear W20524230032022 @default.
• W2052423003 crossrefType "journal-article" @default.
• W2052423003 hasAuthorship W2052423003A5036288870 @default.
• W2052423003 hasAuthorship W2052423003A5046324927 @default.
• W2052423003 hasAuthorship W2052423003A5076308485 @default.
• W2052423003 hasConcept C129374314 @default.
• W2052423003 hasConcept C159047783 @default.
• W2052423003 hasConcept C203014093 @default.
• W2052423003 hasConcept C2776090121 @default.
• W2052423003 hasConcept C2778690821 @default.
• W2052423003 hasConcept C2780252810 @default.
• W2052423003 hasConcept C79484868 @default.
• W2052423003 hasConcept C86803240 @default.
• W2052423003 hasConcept C8891405 @default.
• W2052423003 hasConceptScore W2052423003C129374314 @default.
• W2052423003 hasConceptScore W2052423003C159047783 @default.
• W2052423003 hasConceptScore W2052423003C203014093 @default.
• W2052423003 hasConceptScore W2052423003C2776090121 @default.
• W2052423003 hasConceptScore W2052423003C2778690821 @default.
• W2052423003 hasConceptScore W2052423003C2780252810 @default.
• W2052423003 hasConceptScore W2052423003C79484868 @default.
• W2052423003 hasConceptScore W2052423003C86803240 @default.
• W2052423003 hasConceptScore W2052423003C8891405 @default.
• W2052423003 hasIssue "1-2" @default.
• W2052423003 hasLocation W20524230031 @default.

• next