FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2052463507> ?p ?o ?g. }

• W2052463507 endingPage "11694" @default.
• W2052463507 startingPage "11682" @default.
• W2052463507 abstract "Different cerebellar phenotypes are generated according to a precise spatiotemporal schedule, in which projection neurons precede local interneurons. Glutamatergic neurons develop from the rhombic lip, whereas GABAergic neurons originate from the ventricular neuroepithelium. Progenitors in these germinal layers are committed toward specific phenotypes already at early ontogenetic stages. GABAergic interneurons are thought to derive from a subset of ventricular zone cells, which migrate in the white matter and proliferate up to postnatal life. During this period, different interneuron categories are produced according to an inside-out sequence, from the deep nuclei to the molecular layer (we show here that nuclear interneurons are also born during late embryonic and early postnatal days, after glutamatergic and GABAergic projection neurons). To ask whether distinct interneuron phenotypes share common precursors or derive from multiple fate-restricted progenitors, we examined the behavior of embryonic and postnatal rat cerebellar cells heterotopically/heterochronically transplanted to syngenic hosts. In all conditions, donor cells achieved a high degree of integration in the cerebellar cortex and deep nuclei and acquired GABAergic interneuron phenotypes appropriate for the host age and engraftment site. Therefore, contrary to other cerebellar types, which derive from dedicated precursors, GABAergic interneurons are produced by a common pool of progenitors, which maintain their full developmental potentialities up to late ontogenetic stages and adopt mature identities in response to local instructive cues. In this way, the numbers and types of inhibitory interneurons can be set by spatiotemporally patterned signals to match the functional requirements of developing cerebellar circuits." @default.
• W2052463507 created "2016-06-24" @default.
• W2052463507 creator A5021748161 @default.
• W2052463507 creator A5053173157 @default.
• W2052463507 creator A5066532443 @default.
• W2052463507 creator A5079700241 @default.
• W2052463507 creator A5090350471 @default.
• W2052463507 date "2006-11-08" @default.
• W2052463507 modified "2023-10-11" @default.
• W2052463507 title "Different Types of Cerebellar GABAergic Interneurons Originate from a Common Pool of Multipotent Progenitor Cells" @default.
• W2052463507 cites W124687361 @default.
• W2052463507 cites W1510726759 @default.
• W2052463507 cites W1596826253 @default.
• W2052463507 cites W1604052746 @default.
• W2052463507 cites W1766321086 @default.
• W2052463507 cites W1860779656 @default.
• W2052463507 cites W1964907693 @default.
• W2052463507 cites W1966667764 @default.
• W2052463507 cites W1967337983 @default.
• W2052463507 cites W1973563725 @default.
• W2052463507 cites W1975639021 @default.
• W2052463507 cites W1975858840 @default.
• W2052463507 cites W1976217132 @default.
• W2052463507 cites W1980812563 @default.
• W2052463507 cites W1981431833 @default.
• W2052463507 cites W1982018791 @default.
• W2052463507 cites W1985909952 @default.
• W2052463507 cites W1987107175 @default.
• W2052463507 cites W1989158513 @default.
• W2052463507 cites W1990016096 @default.
• W2052463507 cites W1993042393 @default.
• W2052463507 cites W1993646910 @default.
• W2052463507 cites W2000156766 @default.
• W2052463507 cites W2000918925 @default.
• W2052463507 cites W2001056945 @default.
• W2052463507 cites W2001142544 @default.
• W2052463507 cites W2001704317 @default.
• W2052463507 cites W2003921114 @default.
• W2052463507 cites W2004054097 @default.
• W2052463507 cites W2021746032 @default.
• W2052463507 cites W2022274052 @default.
• W2052463507 cites W2023357131 @default.
• W2052463507 cites W2029232999 @default.
• W2052463507 cites W2030785601 @default.
• W2052463507 cites W2031861229 @default.
• W2052463507 cites W2036555186 @default.
• W2052463507 cites W2041160829 @default.
• W2052463507 cites W2041598409 @default.
• W2052463507 cites W2043500082 @default.
• W2052463507 cites W2046445123 @default.
• W2052463507 cites W2059241101 @default.
• W2052463507 cites W2061614102 @default.
• W2052463507 cites W2066136635 @default.
• W2052463507 cites W2077397037 @default.
• W2052463507 cites W2077686105 @default.
• W2052463507 cites W2080675269 @default.
• W2052463507 cites W2088475496 @default.
• W2052463507 cites W2090875715 @default.
• W2052463507 cites W2100826819 @default.
• W2052463507 cites W2102623650 @default.
• W2052463507 cites W2104380910 @default.
• W2052463507 cites W2109214564 @default.
• W2052463507 cites W2116481437 @default.
• W2052463507 cites W2117711783 @default.
• W2052463507 cites W2135601074 @default.
• W2052463507 cites W2145558392 @default.
• W2052463507 cites W2156625231 @default.
• W2052463507 cites W2158496649 @default.
• W2052463507 cites W2161396457 @default.
• W2052463507 cites W2181633782 @default.
• W2052463507 cites W2188474087 @default.
• W2052463507 cites W2415676249 @default.
• W2052463507 cites W2479691156 @default.
• W2052463507 cites W2506421807 @default.
• W2052463507 cites W2581259096 @default.
• W2052463507 cites W4245552230 @default.
• W2052463507 doi "https://doi.org/10.1523/jneurosci.3656-06.2006" @default.
• W2052463507 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6674781" @default.
• W2052463507 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17093090" @default.
• W2052463507 hasPublicationYear "2006" @default.
• W2052463507 type Work @default.
• W2052463507 sameAs 2052463507 @default.
• W2052463507 citedByCount "155" @default.
• W2052463507 countsByYear W20524635072012 @default.
• W2052463507 countsByYear W20524635072013 @default.
• W2052463507 countsByYear W20524635072014 @default.
• W2052463507 countsByYear W20524635072015 @default.
• W2052463507 countsByYear W20524635072016 @default.
• W2052463507 countsByYear W20524635072017 @default.
• W2052463507 countsByYear W20524635072018 @default.
• W2052463507 countsByYear W20524635072019 @default.
• W2052463507 countsByYear W20524635072020 @default.
• W2052463507 countsByYear W20524635072021 @default.
• W2052463507 countsByYear W20524635072022 @default.
• W2052463507 countsByYear W20524635072023 @default.
• W2052463507 crossrefType "journal-article" @default.
• W2052463507 hasAuthorship W2052463507A5021748161 @default.
• W2052463507 hasAuthorship W2052463507A5053173157 @default.

• next