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- W2052505973 abstract "Abstract— An enzymatic isotopic assay for the measurement of β-phenylethylamine in brain, with a sensitivity of 100-200 pg, has been developed. With this assay, the endogenous β-phenylethylamine content (1.5 ng/g) in the rat brain has been determined. Phenylalanine administration increases the brain levels of this amine; inhibition of monoamine oxidase causes a 40-fold increase in brain β-phenylethylamine. After a combined treatment with a monoamine oxidase inhibitor and phenylalanine, the β-phenylethylamine content in the brain increases to about 400-fold. This increase can be blocked by the central decarboxylase inhibitor NSD-1055. p-Chlorophenylalanine also increases β-phenylethylamipe concentration in the brain, and this effect is potentiated by a simultaneous administration of phenylalanine." @default.
- W2052505973 created "2016-06-24" @default.
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- W2052505973 date "1974-02-01" @default.
- W2052505973 modified "2023-10-10" @default.
- W2052505973 title "ENZYMATIC ISOTOPIC ASSAY FOR AND PRESENCE OF ?-PHENYLETHYLAMINE IN BRAIN" @default.
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- W2052505973 doi "https://doi.org/10.1111/j.1471-4159.1974.tb11581.x" @default.
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