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• W2052514587 abstract "Integration host factor (IHF) of Escherichia coli is an asymmetric histone-like protein that binds and bends the DNA at specific sequences. IHF functions as an accessory factor in a wide variety of processes including replication, site-specific recombination and transcription. In many of these processes IHF was shown to act as an architectural element which helps the formation of nucleo-protein complexes by bending of the DNA at specific sites. This MicroReview shows how such a structural role of IHF can influence the initiation of transcription. In addition, it summarizes the evidence indicating that IHF can stimulate transcription via a direct interaction with RNA polymerase and explores the possibility that the asymmetry of the IHF protein might reflect such an interaction" @default.
• W2052514587 created "2016-06-24" @default.
• W2052514587 creator A5013285403 @default.
• W2052514587 creator A5069611848 @default.
• W2052514587 date "1995-04-01" @default.
• W2052514587 modified "2023-10-10" @default.
• W2052514587 title "The regulation of transcription initiation by integration host factor" @default.
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• W2052514587 doi "https://doi.org/10.1111/j.1365-2958.1995.tb02386.x" @default.
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