FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2052562810> ?p ?o ?g. }

• W2052562810 endingPage "2469" @default.
• W2052562810 startingPage "2462" @default.
• W2052562810 abstract "Motion interplay can affect the tumor dose in scanned proton beam therapy. This study assesses the ability of rescanning and gating to mitigate interplay effects during lung treatments.The treatments of five lung cancer patients [48 Gy(RBE)/4fx] with varying tumor size (21.1-82.3 cm(3)) and motion amplitude (2.9-30.6 mm) were simulated employing 4D Monte Carlo. The authors investigated two spot sizes (σ ∼ 12 and ∼ 3 mm), three rescanning techniques (layered, volumetric, breath-sampled volumetric) and respiratory gating with a 30% duty cycle.For 4/5 patients, layered rescanning 6/2 times (for the small/large spot size) maintains equivalent uniform dose within the target >98% for a single fraction. Breath sampling the timing of rescanning is ∼ 2 times more effective than the same number of continuous rescans. Volumetric rescanning is sensitive to synchronization effects, which was observed in 3/5 patients, though not for layered rescanning. For the large spot size, rescanning compared favorably with gating in terms of time requirements, i.e., 2x-rescanning is on average a factor ∼ 2.6 faster than gating for this scenario. For the small spot size however, 6x-rescanning takes on average 65% longer compared to gating. Rescanning has no effect on normal lung V20 and mean lung dose (MLD), though it reduces the maximum lung dose by on average 6.9 ± 2.4/16.7 ± 12.2 Gy(RBE) for the large and small spot sizes, respectively. Gating leads to a similar reduction in maximum dose and additionally reduces V20 and MLD. Breath-sampled rescanning is most successful in reducing the maximum dose to the normal lung.Both rescanning (2-6 times, depending on the beam size) as well as gating was able to mitigate interplay effects in the target for 4/5 patients studied. Layered rescanning is superior to volumetric rescanning, as the latter suffers from synchronization effects in 3/5 patients studied. Gating minimizes the irradiated volume of normal lung more efficiently, while breath-sampled rescanning is superior in reducing maximum doses to organs at risk." @default.
• W2052562810 created "2016-06-24" @default.
• W2052562810 creator A5037938903 @default.
• W2052562810 creator A5065983899 @default.
• W2052562810 creator A5072499473 @default.
• W2052562810 creator A5090315641 @default.
• W2052562810 date "2015-05-01" @default.
• W2052562810 modified "2023-10-14" @default.
• W2052562810 title "Motion mitigation for lung cancer patients treated with active scanning proton therapy" @default.
• W2052562810 cites W1965242704 @default.
• W2052562810 cites W1978103445 @default.
• W2052562810 cites W1983490139 @default.
• W2052562810 cites W1987134214 @default.
• W2052562810 cites W1989301920 @default.
• W2052562810 cites W1989885502 @default.
• W2052562810 cites W1995766420 @default.
• W2052562810 cites W2009537834 @default.
• W2052562810 cites W2025974108 @default.
• W2052562810 cites W2030544564 @default.
• W2052562810 cites W2037171241 @default.
• W2052562810 cites W2051756045 @default.
• W2052562810 cites W2059950254 @default.
• W2052562810 cites W2071042777 @default.
• W2052562810 cites W2077910495 @default.
• W2052562810 cites W2078763031 @default.
• W2052562810 cites W2093338140 @default.
• W2052562810 cites W2103551282 @default.
• W2052562810 cites W2124005644 @default.
• W2052562810 cites W2133147741 @default.
• W2052562810 cites W2133766120 @default.
• W2052562810 cites W2155758197 @default.
• W2052562810 doi "https://doi.org/10.1118/1.4916662" @default.
• W2052562810 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4409624" @default.
• W2052562810 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25979039" @default.
• W2052562810 hasPublicationYear "2015" @default.
• W2052562810 type Work @default.
• W2052562810 sameAs 2052562810 @default.
• W2052562810 citedByCount "73" @default.
• W2052562810 countsByYear W20525628102015 @default.
• W2052562810 countsByYear W20525628102016 @default.
• W2052562810 countsByYear W20525628102017 @default.
• W2052562810 countsByYear W20525628102018 @default.
• W2052562810 countsByYear W20525628102019 @default.
• W2052562810 countsByYear W20525628102020 @default.
• W2052562810 countsByYear W20525628102021 @default.
• W2052562810 countsByYear W20525628102022 @default.
• W2052562810 countsByYear W20525628102023 @default.
• W2052562810 crossrefType "journal-article" @default.
• W2052562810 hasAuthorship W2052562810A5037938903 @default.
• W2052562810 hasAuthorship W2052562810A5065983899 @default.
• W2052562810 hasAuthorship W2052562810A5072499473 @default.
• W2052562810 hasAuthorship W2052562810A5090315641 @default.
• W2052562810 hasBestOaLocation W20525628102 @default.
• W2052562810 hasConcept C120665830 @default.
• W2052562810 hasConcept C121332964 @default.
• W2052562810 hasConcept C136229726 @default.
• W2052562810 hasConcept C165801399 @default.
• W2052562810 hasConcept C168834538 @default.
• W2052562810 hasConcept C194544171 @default.
• W2052562810 hasConcept C199822604 @default.
• W2052562810 hasConcept C2779244869 @default.
• W2052562810 hasConcept C2989005 @default.
• W2052562810 hasConcept C42407357 @default.
• W2052562810 hasConcept C62520636 @default.
• W2052562810 hasConcept C71924100 @default.
• W2052562810 hasConceptScore W2052562810C120665830 @default.
• W2052562810 hasConceptScore W2052562810C121332964 @default.
• W2052562810 hasConceptScore W2052562810C136229726 @default.
• W2052562810 hasConceptScore W2052562810C165801399 @default.
• W2052562810 hasConceptScore W2052562810C168834538 @default.
• W2052562810 hasConceptScore W2052562810C194544171 @default.
• W2052562810 hasConceptScore W2052562810C199822604 @default.
• W2052562810 hasConceptScore W2052562810C2779244869 @default.
• W2052562810 hasConceptScore W2052562810C2989005 @default.
• W2052562810 hasConceptScore W2052562810C42407357 @default.
• W2052562810 hasConceptScore W2052562810C62520636 @default.
• W2052562810 hasConceptScore W2052562810C71924100 @default.
• W2052562810 hasFunder F4320332161 @default.
• W2052562810 hasIssue "5" @default.
• W2052562810 hasLocation W20525628101 @default.
• W2052562810 hasLocation W20525628102 @default.
• W2052562810 hasLocation W20525628103 @default.
• W2052562810 hasLocation W20525628104 @default.
• W2052562810 hasOpenAccess W2052562810 @default.
• W2052562810 hasPrimaryLocation W20525628101 @default.
• W2052562810 hasRelatedWork W1991585727 @default.
• W2052562810 hasRelatedWork W2031449089 @default.
• W2052562810 hasRelatedWork W2072696177 @default.
• W2052562810 hasRelatedWork W2112596406 @default.
• W2052562810 hasRelatedWork W2125499229 @default.
• W2052562810 hasRelatedWork W2410610877 @default.
• W2052562810 hasRelatedWork W4385304246 @default.
• W2052562810 hasRelatedWork W4387096018 @default.
• W2052562810 hasRelatedWork W4387096070 @default.
• W2052562810 hasRelatedWork W4387096269 @default.
• W2052562810 hasVolume "42" @default.
• W2052562810 isParatext "false" @default.
• W2052562810 isRetracted "false" @default.

• next