Matches in SemOpenAlex for { <https://semopenalex.org/work/W2052566511> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2052566511 endingPage "681" @default.
- W2052566511 startingPage "676" @default.
- W2052566511 abstract "Tuberculosis is still one of the most important cause of mortality and morbidity in many countries and there is a need for new methods for accurate and rapid diagnosis of tuberculosis. To determine the sensitivity and specificity of polymerase chain reaction (PCR) method, we have evaluated Mycobacterium tuberculosis DNA in peripheral blood samples with PCR technique in adult patients with human immunodeficiency virus (HIV)-negative and new cases of smear-positive pulmonary tuberculosis. We investigated the relationship between characteristic of the patients, radiological extension of the disease, sputum smear grade, presence of cavity, body-mass index (BMI) serum albumin level, total delay time and PCR positivity. Forty patients (33 male and 7 female; mean age 37.8 +/- 14.1) and 20 healthy control subjects (13 male and 7 female; mean age 35.6 +/- 7.3) were enrolled in this study. PCR was positive in 16 of 40 (40%) patients with pulmonary tuberculosis and negative in 24 of 40 (60%). None of the healthy controls had positive PCR results. The overall sensitivity specificity and accuracy of the PCR assay was 40, 100 and 60%, respectively. We found the positive correlation between PCR positivity and sputum smear grade (r=0.46, P=0.003) radiological extension of the disease (r=0.69, P=0.001), presence of cavity (r=0.90, P=0.001). We conclude that the detection of M. tuberculosis DNA from peripheral blood by PCR technique is useful for the rapid diagnosis of tuberculosis patients with HIV-negative. Hematogenous dissemination was important in tuberculosis patients and peripheral blood samples were suitable and easy materials. However, standardization of the PCR method must be ensured for the diagnosis of tuberculosis." @default.
- W2052566511 created "2016-06-24" @default.
- W2052566511 creator A5002812942 @default.
- W2052566511 creator A5022811284 @default.
- W2052566511 creator A5029432045 @default.
- W2052566511 creator A5053146208 @default.
- W2052566511 creator A5087945755 @default.
- W2052566511 date "2003-06-01" @default.
- W2052566511 modified "2023-09-25" @default.
- W2052566511 title "Detection of Mycobacterium Tuberculosis DNA from peripheral blood in patients with HIV-seronegative and new cases of smear-positive pulmonary tuberculosis by polymerase chain reaction" @default.
- W2052566511 cites W1554254953 @default.
- W2052566511 cites W1881197443 @default.
- W2052566511 cites W1902197668 @default.
- W2052566511 cites W1963938546 @default.
- W2052566511 cites W1981509297 @default.
- W2052566511 cites W2000620558 @default.
- W2052566511 cites W2003864032 @default.
- W2052566511 cites W2058342738 @default.
- W2052566511 cites W2077022677 @default.
- W2052566511 cites W2081087219 @default.
- W2052566511 cites W2107832992 @default.
- W2052566511 cites W2109604991 @default.
- W2052566511 cites W2119453720 @default.
- W2052566511 cites W2165292733 @default.
- W2052566511 cites W2170457111 @default.
- W2052566511 doi "https://doi.org/10.1053/rmed.2003.1500" @default.
- W2052566511 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12814154" @default.
- W2052566511 hasPublicationYear "2003" @default.
- W2052566511 type Work @default.
- W2052566511 sameAs 2052566511 @default.
- W2052566511 citedByCount "17" @default.
- W2052566511 countsByYear W20525665112012 @default.
- W2052566511 countsByYear W20525665112013 @default.
- W2052566511 countsByYear W20525665112014 @default.
- W2052566511 countsByYear W20525665112016 @default.
- W2052566511 countsByYear W20525665112019 @default.
- W2052566511 countsByYear W20525665112022 @default.
- W2052566511 countsByYear W20525665112023 @default.
- W2052566511 crossrefType "journal-article" @default.
- W2052566511 hasAuthorship W2052566511A5002812942 @default.
- W2052566511 hasAuthorship W2052566511A5022811284 @default.
- W2052566511 hasAuthorship W2052566511A5029432045 @default.
- W2052566511 hasAuthorship W2052566511A5053146208 @default.
- W2052566511 hasAuthorship W2052566511A5087945755 @default.
- W2052566511 hasBestOaLocation W20525665111 @default.
- W2052566511 hasConcept C104317684 @default.
- W2052566511 hasConcept C126322002 @default.
- W2052566511 hasConcept C142724271 @default.
- W2052566511 hasConcept C203014093 @default.
- W2052566511 hasConcept C2776301714 @default.
- W2052566511 hasConcept C2777975735 @default.
- W2052566511 hasConcept C2781069245 @default.
- W2052566511 hasConcept C49105822 @default.
- W2052566511 hasConcept C55493867 @default.
- W2052566511 hasConcept C71924100 @default.
- W2052566511 hasConcept C86803240 @default.
- W2052566511 hasConcept C90924648 @default.
- W2052566511 hasConceptScore W2052566511C104317684 @default.
- W2052566511 hasConceptScore W2052566511C126322002 @default.
- W2052566511 hasConceptScore W2052566511C142724271 @default.
- W2052566511 hasConceptScore W2052566511C203014093 @default.
- W2052566511 hasConceptScore W2052566511C2776301714 @default.
- W2052566511 hasConceptScore W2052566511C2777975735 @default.
- W2052566511 hasConceptScore W2052566511C2781069245 @default.
- W2052566511 hasConceptScore W2052566511C49105822 @default.
- W2052566511 hasConceptScore W2052566511C55493867 @default.
- W2052566511 hasConceptScore W2052566511C71924100 @default.
- W2052566511 hasConceptScore W2052566511C86803240 @default.
- W2052566511 hasConceptScore W2052566511C90924648 @default.
- W2052566511 hasIssue "6" @default.
- W2052566511 hasLocation W20525665111 @default.
- W2052566511 hasLocation W20525665112 @default.
- W2052566511 hasOpenAccess W2052566511 @default.
- W2052566511 hasPrimaryLocation W20525665111 @default.
- W2052566511 hasRelatedWork W1973643715 @default.
- W2052566511 hasRelatedWork W2119745045 @default.
- W2052566511 hasRelatedWork W2148851929 @default.
- W2052566511 hasRelatedWork W2396781166 @default.
- W2052566511 hasRelatedWork W2419578151 @default.
- W2052566511 hasRelatedWork W2441872429 @default.
- W2052566511 hasRelatedWork W2782996837 @default.
- W2052566511 hasRelatedWork W2862367420 @default.
- W2052566511 hasRelatedWork W3165151283 @default.
- W2052566511 hasRelatedWork W4308058527 @default.
- W2052566511 hasVolume "97" @default.
- W2052566511 isParatext "false" @default.
- W2052566511 isRetracted "false" @default.
- W2052566511 magId "2052566511" @default.
- W2052566511 workType "article" @default.