FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2052590951> ?p ?o ?g. }

• W2052590951 endingPage "299" @default.
• W2052590951 startingPage "292" @default.
• W2052590951 abstract "The skin of the third trimester fetus and early newborn exhibits a complex, multifunctional, highly hydrated but viscous skin-surface biofilm called vernix caseosa (VC). During birth, VC undergoes a substantial change from an aqueous and warm surrounding into a gaseous and colder environment postnatally. The aim of this study was to investigate the structural and physicochemical changes in VC, which accompany physiologically relevant variations in environment parameters, such as temperature and humidity. A remarkable difference was observed in water release and uptake properties: dehydration and rehydration processes take place two to four times faster at 37°C than at room temperature (RT). The dehydration was irreversible; rehydration was only possible to a final weight of 55% (37°C) and 46% (RT) of the pre-desiccation weight. Differential scanning calorimetry showed two different overlapping phase transitions within physiological temperature range. Investigation of the lipid organization by Fourier transform infrared spectroscopy and small-angle X-ray diffraction revealed a more disordered state of lipids at 37°C than at RT, which might explain the faster dehydration and rehydration process at 37°C as well as the changes in thermotropic rheological behavior. In conclusion, we demonstrated that VC properties adjust to the fundamental change from the intrauterine to the post-natal environment. The skin of the third trimester fetus and early newborn exhibits a complex, multifunctional, highly hydrated but viscous skin-surface biofilm called vernix caseosa (VC). During birth, VC undergoes a substantial change from an aqueous and warm surrounding into a gaseous and colder environment postnatally. The aim of this study was to investigate the structural and physicochemical changes in VC, which accompany physiologically relevant variations in environment parameters, such as temperature and humidity. A remarkable difference was observed in water release and uptake properties: dehydration and rehydration processes take place two to four times faster at 37°C than at room temperature (RT). The dehydration was irreversible; rehydration was only possible to a final weight of 55% (37°C) and 46% (RT) of the pre-desiccation weight. Differential scanning calorimetry showed two different overlapping phase transitions within physiological temperature range. Investigation of the lipid organization by Fourier transform infrared spectroscopy and small-angle X-ray diffraction revealed a more disordered state of lipids at 37°C than at RT, which might explain the faster dehydration and rehydration process at 37°C as well as the changes in thermotropic rheological behavior. In conclusion, we demonstrated that VC properties adjust to the fundamental change from the intrauterine to the post-natal environment. cryo-scanning electron microscopy differential scanning calorimetry Fourier transform infrared spectroscopy room temperature small-angle X-ray diffraction stratum corneum vernix caseosa" @default.
• W2052590951 created "2016-06-24" @default.
• W2052590951 creator A5017735982 @default.
• W2052590951 creator A5025078821 @default.
• W2052590951 creator A5048949420 @default.
• W2052590951 creator A5054836944 @default.
• W2052590951 creator A5056426915 @default.
• W2052590951 creator A5072790675 @default.
• W2052590951 creator A5073070631 @default.
• W2052590951 date "2008-02-01" @default.
• W2052590951 modified "2023-10-03" @default.
• W2052590951 title "Temperature-Induced Changes in Structural and Physicochemical Properties of Vernix Caseosa" @default.
• W2052590951 cites W1971992928 @default.
• W2052590951 cites W1977349496 @default.
• W2052590951 cites W1980077165 @default.
• W2052590951 cites W1984090841 @default.
• W2052590951 cites W1985688513 @default.
• W2052590951 cites W1996592974 @default.
• W2052590951 cites W2014055627 @default.
• W2052590951 cites W2030946035 @default.
• W2052590951 cites W2033214402 @default.
• W2052590951 cites W2041608291 @default.
• W2052590951 cites W2045098982 @default.
• W2052590951 cites W2054873632 @default.
• W2052590951 cites W2058964528 @default.
• W2052590951 cites W2059875770 @default.
• W2052590951 cites W2069185355 @default.
• W2052590951 cites W2084787688 @default.
• W2052590951 cites W2085183163 @default.
• W2052590951 cites W2091422866 @default.
• W2052590951 cites W2123308506 @default.
• W2052590951 cites W2129393221 @default.
• W2052590951 cites W2135693586 @default.
• W2052590951 cites W2156071020 @default.
• W2052590951 doi "https://doi.org/10.1038/sj.jid.5701022" @default.
• W2052590951 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17671513" @default.
• W2052590951 hasPublicationYear "2008" @default.
• W2052590951 type Work @default.
• W2052590951 sameAs 2052590951 @default.
• W2052590951 citedByCount "15" @default.
• W2052590951 countsByYear W20525909512014 @default.
• W2052590951 countsByYear W20525909512015 @default.
• W2052590951 countsByYear W20525909512018 @default.
• W2052590951 countsByYear W20525909512020 @default.
• W2052590951 countsByYear W20525909512023 @default.
• W2052590951 crossrefType "journal-article" @default.
• W2052590951 hasAuthorship W2052590951A5017735982 @default.
• W2052590951 hasAuthorship W2052590951A5025078821 @default.
• W2052590951 hasAuthorship W2052590951A5048949420 @default.
• W2052590951 hasAuthorship W2052590951A5054836944 @default.
• W2052590951 hasAuthorship W2052590951A5056426915 @default.
• W2052590951 hasAuthorship W2052590951A5072790675 @default.
• W2052590951 hasAuthorship W2052590951A5073070631 @default.
• W2052590951 hasBestOaLocation W20525909511 @default.
• W2052590951 hasConcept C121332964 @default.
• W2052590951 hasConcept C12554922 @default.
• W2052590951 hasConcept C151420433 @default.
• W2052590951 hasConcept C172680121 @default.
• W2052590951 hasConcept C178790620 @default.
• W2052590951 hasConcept C184651966 @default.
• W2052590951 hasConcept C185592680 @default.
• W2052590951 hasConcept C22064058 @default.
• W2052590951 hasConcept C2778769901 @default.
• W2052590951 hasConcept C2779234561 @default.
• W2052590951 hasConcept C2994273327 @default.
• W2052590951 hasConcept C39519442 @default.
• W2052590951 hasConcept C44280652 @default.
• W2052590951 hasConcept C54355233 @default.
• W2052590951 hasConcept C55493867 @default.
• W2052590951 hasConcept C86803240 @default.
• W2052590951 hasConcept C97355855 @default.
• W2052590951 hasConceptScore W2052590951C121332964 @default.
• W2052590951 hasConceptScore W2052590951C12554922 @default.
• W2052590951 hasConceptScore W2052590951C151420433 @default.
• W2052590951 hasConceptScore W2052590951C172680121 @default.
• W2052590951 hasConceptScore W2052590951C178790620 @default.
• W2052590951 hasConceptScore W2052590951C184651966 @default.
• W2052590951 hasConceptScore W2052590951C185592680 @default.
• W2052590951 hasConceptScore W2052590951C22064058 @default.
• W2052590951 hasConceptScore W2052590951C2778769901 @default.
• W2052590951 hasConceptScore W2052590951C2779234561 @default.
• W2052590951 hasConceptScore W2052590951C2994273327 @default.
• W2052590951 hasConceptScore W2052590951C39519442 @default.
• W2052590951 hasConceptScore W2052590951C44280652 @default.
• W2052590951 hasConceptScore W2052590951C54355233 @default.
• W2052590951 hasConceptScore W2052590951C55493867 @default.
• W2052590951 hasConceptScore W2052590951C86803240 @default.
• W2052590951 hasConceptScore W2052590951C97355855 @default.
• W2052590951 hasIssue "2" @default.
• W2052590951 hasLocation W20525909511 @default.
• W2052590951 hasLocation W20525909512 @default.
• W2052590951 hasOpenAccess W2052590951 @default.
• W2052590951 hasPrimaryLocation W20525909511 @default.
• W2052590951 hasRelatedWork W1990763317 @default.
• W2052590951 hasRelatedWork W1993602513 @default.
• W2052590951 hasRelatedWork W2043639745 @default.
• W2052590951 hasRelatedWork W2049926299 @default.
• W2052590951 hasRelatedWork W2147692435 @default.

• next