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• W2052596902 abstract "It has been suggested that vitamin D 2 is not very prevalent in the human food chain. However, data from a number of recent intervention studies suggest that the majority of subjects had measurable serum 25-hydroxyvitamin D 2 (25(OH)D 2 ) concentrations. Serum 25(OH)D 2 , unlike 25(OH)D 3 , is not directly influenced by exposure of skin to sun and thus has dietary origins; however, quantifying dietary vitamin D 2 is difficult due to the limitations of food composition data. Therefore, the present study aimed to characterise serum 25(OH)D 2 concentrations in the participants of the National Adult Nutrition Survey (NANS) in Ireland, and to use these serum concentrations to estimate the intake of vitamin D 2 using a mathematical modelling approach. Serum 25(OH)D 2 concentration was measured by a liquid chromatography–tandem MS method, and information on diet as well as subject characteristics was obtained from the NANS. Of these participants, 78·7 % ( n 884) had serum 25(OH)D 2 concentrations above the limit of quantification, and the mean, maximum, 10th, 50th (median) and 90th percentile values of serum 25(OH)D 2 concentrations were 3·69, 27·6, 1·71, 2·96 and 6·36 nmol/l, respectively. To approximate the intake of vitamin D 2 from these serum 25(OH)D 2 concentrations, we used recently published data on the relationship between vitamin D intake and the responses of serum 25(OH)D concentrations. The projected 5th to 95th percentile intakes of vitamin D 2 for adults were in the range of 0·9–1·2 and 5–6 μg/d, respectively, and the median intake ranged from 1·7 to 2·3 μg/d. In conclusion, the present data demonstrate that 25(OH)D 2 concentrations are present in the sera of adults from this nationally representative sample. Vitamin D 2 may have an impact on nutritional adequacy at a population level and thus warrants further investigation." @default.
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• W2052596902 date "2014-04-29" @default.
• W2052596902 modified "2023-09-24" @default.
• W2052596902 title "Dietary vitamin D₂ – a potentially underestimated contributor to vitamin D nutritional status of adults?" @default.
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• W2052596902 doi "https://doi.org/10.1017/s0007114514000725" @default.
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