FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2052602181> ?p ?o ?g. }

• W2052602181 endingPage "714" @default.
• W2052602181 startingPage "711" @default.
• W2052602181 abstract "Extended 24-hour pH monitoring and esophagealmanometry before and 6 months after Nissen fundoplication in a group of 14 children with symptomatic gastroesophageal reflux (GER), of whom 12 had esophagitis, have shown that (1) all patients were clinically cured and their initially abnormal pH-monitoring parameters significantly decreased to normal values after operation. (2) Whereas lower esophageal sphincter pressure (LESP) was not modified by surgery, lower esophageal sphincter length (LESL) was significantly increased. (3) The percentage of tertiary, nonpropulsive esophageal waves, that was very high in basal conditions (74.9±34.5%) and following instillation of acid into the esophagus (79.8±20.2%) remained high (58±23.2% and 72.1±18.2% respectively) several months postoperatively. The persistence of abnormal peristalsis after surgical cure of GER suggests that severe symptoms in this group of patients resulted from the simultaneous failure of both components of the antireflux mechanism (LES and esophageal peristaltic “pump”), which led to increased acid exposure. The good results of surgical establishment of an effective valve-like barrier alone illustrate the possibility of compensation by only one of the components when the other fails. According to this interpretation, whereas patients with good peristalsis would tolerate GER fairly well, those with GER and bad peristalsis would have increased acid exposure and, consequently, esophageal damage. Extended 24-hour pH monitoring and esophagealmanometry before and 6 months after Nissen fundoplication in a group of 14 children with symptomatic gastroesophageal reflux (GER), of whom 12 had esophagitis, have shown that (1) all patients were clinically cured and their initially abnormal pH-monitoring parameters significantly decreased to normal values after operation. (2) Whereas lower esophageal sphincter pressure (LESP) was not modified by surgery, lower esophageal sphincter length (LESL) was significantly increased. (3) The percentage of tertiary, nonpropulsive esophageal waves, that was very high in basal conditions (74.9±34.5%) and following instillation of acid into the esophagus (79.8±20.2%) remained high (58±23.2% and 72.1±18.2% respectively) several months postoperatively. The persistence of abnormal peristalsis after surgical cure of GER suggests that severe symptoms in this group of patients resulted from the simultaneous failure of both components of the antireflux mechanism (LES and esophageal peristaltic “pump”), which led to increased acid exposure. The good results of surgical establishment of an effective valve-like barrier alone illustrate the possibility of compensation by only one of the components when the other fails. According to this interpretation, whereas patients with good peristalsis would tolerate GER fairly well, those with GER and bad peristalsis would have increased acid exposure and, consequently, esophageal damage." @default.
• W2052602181 created "2016-06-24" @default.
• W2052602181 creator A5007642129 @default.
• W2052602181 creator A5043878107 @default.
• W2052602181 creator A5054948837 @default.
• W2052602181 date "1986-08-01" @default.
• W2052602181 modified "2023-10-14" @default.
• W2052602181 title "Abnormal preoperative and postoperative esophageal peristalsis in gastroesophageal reflux" @default.
• W2052602181 cites W113162249 @default.
• W2052602181 cites W1486437211 @default.
• W2052602181 cites W1549523908 @default.
• W2052602181 cites W1564752197 @default.
• W2052602181 cites W1834887135 @default.
• W2052602181 cites W1969656869 @default.
• W2052602181 cites W1971055455 @default.
• W2052602181 cites W1995153593 @default.
• W2052602181 cites W2023143183 @default.
• W2052602181 cites W2045074533 @default.
• W2052602181 cites W2060225288 @default.
• W2052602181 cites W2067647246 @default.
• W2052602181 cites W2072489404 @default.
• W2052602181 cites W2078257464 @default.
• W2052602181 cites W2088339249 @default.
• W2052602181 cites W2418680661 @default.
• W2052602181 cites W2471757571 @default.
• W2052602181 cites W3160639565 @default.
• W2052602181 cites W4205575620 @default.
• W2052602181 cites W4239156471 @default.
• W2052602181 doi "https://doi.org/10.1016/s0022-3468(86)80393-1" @default.
• W2052602181 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3746607" @default.
• W2052602181 hasPublicationYear "1986" @default.
• W2052602181 type Work @default.
• W2052602181 sameAs 2052602181 @default.
• W2052602181 citedByCount "24" @default.
• W2052602181 countsByYear W20526021812012 @default.
• W2052602181 crossrefType "journal-article" @default.
• W2052602181 hasAuthorship W2052602181A5007642129 @default.
• W2052602181 hasAuthorship W2052602181A5043878107 @default.
• W2052602181 hasAuthorship W2052602181A5054948837 @default.
• W2052602181 hasConcept C126322002 @default.
• W2052602181 hasConcept C141071460 @default.
• W2052602181 hasConcept C206813253 @default.
• W2052602181 hasConcept C2777014526 @default.
• W2052602181 hasConcept C2777819096 @default.
• W2052602181 hasConcept C2778024521 @default.
• W2052602181 hasConcept C2779134260 @default.
• W2052602181 hasConcept C2779306644 @default.
• W2052602181 hasConcept C2779920096 @default.
• W2052602181 hasConcept C2779949763 @default.
• W2052602181 hasConcept C2780877482 @default.
• W2052602181 hasConcept C2909576783 @default.
• W2052602181 hasConcept C3018799001 @default.
• W2052602181 hasConcept C43270747 @default.
• W2052602181 hasConcept C71924100 @default.
• W2052602181 hasConcept C90924648 @default.
• W2052602181 hasConceptScore W2052602181C126322002 @default.
• W2052602181 hasConceptScore W2052602181C141071460 @default.
• W2052602181 hasConceptScore W2052602181C206813253 @default.
• W2052602181 hasConceptScore W2052602181C2777014526 @default.
• W2052602181 hasConceptScore W2052602181C2777819096 @default.
• W2052602181 hasConceptScore W2052602181C2778024521 @default.
• W2052602181 hasConceptScore W2052602181C2779134260 @default.
• W2052602181 hasConceptScore W2052602181C2779306644 @default.
• W2052602181 hasConceptScore W2052602181C2779920096 @default.
• W2052602181 hasConceptScore W2052602181C2779949763 @default.
• W2052602181 hasConceptScore W2052602181C2780877482 @default.
• W2052602181 hasConceptScore W2052602181C2909576783 @default.
• W2052602181 hasConceptScore W2052602181C3018799001 @default.
• W2052602181 hasConceptScore W2052602181C43270747 @default.
• W2052602181 hasConceptScore W2052602181C71924100 @default.
• W2052602181 hasConceptScore W2052602181C90924648 @default.
• W2052602181 hasIssue "8" @default.
• W2052602181 hasLocation W20526021811 @default.
• W2052602181 hasLocation W20526021812 @default.
• W2052602181 hasOpenAccess W2052602181 @default.
• W2052602181 hasPrimaryLocation W20526021811 @default.
• W2052602181 hasRelatedWork W1555429862 @default.
• W2052602181 hasRelatedWork W1991680875 @default.
• W2052602181 hasRelatedWork W1993913814 @default.
• W2052602181 hasRelatedWork W2069307024 @default.
• W2052602181 hasRelatedWork W2270879060 @default.
• W2052602181 hasRelatedWork W2395622830 @default.
• W2052602181 hasRelatedWork W2412891642 @default.
• W2052602181 hasRelatedWork W2416776974 @default.
• W2052602181 hasRelatedWork W3029277473 @default.
• W2052602181 hasRelatedWork W5989189 @default.
• W2052602181 hasVolume "21" @default.
• W2052602181 isParatext "false" @default.
• W2052602181 isRetracted "false" @default.
• W2052602181 magId "2052602181" @default.
• W2052602181 workType "article" @default.