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- W2052637859 abstract "The partition of the amphiphile Sodium Dodecyl Sulfate between an aqueous solution and a POPC bilayer was followed by ITC as a function of the total concentration of SDS. It was found that the obtained partition coefficient is strongly affected by the ligand concentration, even after correction for the charge imposed by SDS to the bilayer due to its partition. The partition coefficient decreased as the concentration of SDS increased and this was accompanied by an increase in the molar enthalpy. This behavior is due to saturation of the lipid bilayer leading to non-ideal behavior. Some rules are proposed to enable the retrieval of the parameters that describe the interaction of ligands with unperturbed lipid bilayers." @default.
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- W2052637859 date "2010-01-01" @default.
- W2052637859 modified "2023-09-30" @default.
- W2052637859 title "Partition of Amphiphilic Molecules To Lipid Bilayers By ITC" @default.
- W2052637859 doi "https://doi.org/10.1016/j.bpj.2009.12.451" @default.
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