FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2052669110> ?p ?o ?g. }

• W2052669110 endingPage "331" @default.
• W2052669110 startingPage "325" @default.
• W2052669110 abstract "Polymorphisms in CYP3A genes, such as CYP3A5 and CYP3A4 , as well as in the MDR1 gene, which encodes for P-glycoprotein, have been implicated as genetic markers in several disorders. Differences in the frequency distribution of the allelic variants CYP3A5*3 , CYP3A4*1B , and MDR1 3435T have been demonstrated between distinct ethnic groups. In this study we examined the frequency of these allelic variants in 317 healthy Mestizo individuals from Ecuador and made comparisons with results reported in the literature. The genotypes were determined by PCR-RFLP. Allele and genotype differences were studied by chi-square test. The MDR1 T allele frequency was similar to that of Spaniard or Asian populations, which is consistent with the ethnic origin of Ecuadorian Mestizo individuals (Amerindian and Spaniard Caucasians). By contrast, the CYP3A5*3 allele frequency was significantly lower in Ecuadorians than in Spaniards and other white populations and higher than in Central Americans, Asians and blacks. CYP3A4*1B was more common in Ecuadorians than in Caucasian or Asian populations but less present than in blacks. The differences in the polymorphism found in this work should be considered in allele-disease association studies." @default.
• W2052669110 created "2016-06-24" @default.
• W2052669110 creator A5002936618 @default.
• W2052669110 creator A5005343996 @default.
• W2052669110 creator A5029429704 @default.
• W2052669110 creator A5030167986 @default.
• W2052669110 creator A5045514688 @default.
• W2052669110 creator A5051274260 @default.
• W2052669110 creator A5071658731 @default.
• W2052669110 date "2008-01-01" @default.
• W2052669110 modified "2023-10-18" @default.
• W2052669110 title "<i>CYP3A5*3</i>,<i>CYP3A4*1B</i>and<i>MDR1</i>C3435T Genotype Distributions in Ecuadorians" @default.
• W2052669110 cites W1505376713 @default.
• W2052669110 cites W1565203547 @default.
• W2052669110 cites W1580465079 @default.
• W2052669110 cites W1965522679 @default.
• W2052669110 cites W1972856183 @default.
• W2052669110 cites W1983785977 @default.
• W2052669110 cites W1989108550 @default.
• W2052669110 cites W1991886667 @default.
• W2052669110 cites W1994027559 @default.
• W2052669110 cites W2000683024 @default.
• W2052669110 cites W2004411083 @default.
• W2052669110 cites W2004770194 @default.
• W2052669110 cites W2017098712 @default.
• W2052669110 cites W2024673186 @default.
• W2052669110 cites W2027254251 @default.
• W2052669110 cites W2033290892 @default.
• W2052669110 cites W2034335509 @default.
• W2052669110 cites W2040634965 @default.
• W2052669110 cites W2043317965 @default.
• W2052669110 cites W2049351187 @default.
• W2052669110 cites W2051371418 @default.
• W2052669110 cites W2053939838 @default.
• W2052669110 cites W2054458932 @default.
• W2052669110 cites W2058215178 @default.
• W2052669110 cites W2061303604 @default.
• W2052669110 cites W2066919313 @default.
• W2052669110 cites W2071732758 @default.
• W2052669110 cites W2078837426 @default.
• W2052669110 cites W2095360463 @default.
• W2052669110 cites W2105009666 @default.
• W2052669110 cites W2105902511 @default.
• W2052669110 cites W2106880751 @default.
• W2052669110 cites W2117944128 @default.
• W2052669110 cites W2126772533 @default.
• W2052669110 cites W2131584305 @default.
• W2052669110 cites W2139066033 @default.
• W2052669110 cites W2143600899 @default.
• W2052669110 cites W2149628392 @default.
• W2052669110 cites W2152445275 @default.
• W2052669110 cites W2153018324 @default.
• W2052669110 cites W2160132117 @default.
• W2052669110 cites W2415156144 @default.
• W2052669110 doi "https://doi.org/10.1155/2008/750804" @default.
• W2052669110 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3850616" @default.
• W2052669110 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18688081" @default.
• W2052669110 hasPublicationYear "2008" @default.
• W2052669110 type Work @default.
• W2052669110 sameAs 2052669110 @default.
• W2052669110 citedByCount "6" @default.
• W2052669110 countsByYear W20526691102016 @default.
• W2052669110 countsByYear W20526691102019 @default.
• W2052669110 countsByYear W20526691102020 @default.
• W2052669110 countsByYear W20526691102021 @default.
• W2052669110 crossrefType "journal-article" @default.
• W2052669110 hasAuthorship W2052669110A5002936618 @default.
• W2052669110 hasAuthorship W2052669110A5005343996 @default.
• W2052669110 hasAuthorship W2052669110A5029429704 @default.
• W2052669110 hasAuthorship W2052669110A5030167986 @default.
• W2052669110 hasAuthorship W2052669110A5045514688 @default.
• W2052669110 hasAuthorship W2052669110A5051274260 @default.
• W2052669110 hasAuthorship W2052669110A5071658731 @default.
• W2052669110 hasBestOaLocation W20526691101 @default.
• W2052669110 hasConcept C104317684 @default.
• W2052669110 hasConcept C135763542 @default.
• W2052669110 hasConcept C137403100 @default.
• W2052669110 hasConcept C149737253 @default.
• W2052669110 hasConcept C175239580 @default.
• W2052669110 hasConcept C17744445 @default.
• W2052669110 hasConcept C180754005 @default.
• W2052669110 hasConcept C199539241 @default.
• W2052669110 hasConcept C37463918 @default.
• W2052669110 hasConcept C54355233 @default.
• W2052669110 hasConcept C86803240 @default.
• W2052669110 hasConcept C92137452 @default.
• W2052669110 hasConceptScore W2052669110C104317684 @default.
• W2052669110 hasConceptScore W2052669110C135763542 @default.
• W2052669110 hasConceptScore W2052669110C137403100 @default.
• W2052669110 hasConceptScore W2052669110C149737253 @default.
• W2052669110 hasConceptScore W2052669110C175239580 @default.
• W2052669110 hasConceptScore W2052669110C17744445 @default.
• W2052669110 hasConceptScore W2052669110C180754005 @default.
• W2052669110 hasConceptScore W2052669110C199539241 @default.
• W2052669110 hasConceptScore W2052669110C37463918 @default.
• W2052669110 hasConceptScore W2052669110C54355233 @default.
• W2052669110 hasConceptScore W2052669110C86803240 @default.
• W2052669110 hasConceptScore W2052669110C92137452 @default.

• next