FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2052768082> ?p ?o ?g. }

• W2052768082 endingPage "1939" @default.
• W2052768082 startingPage "1933" @default.
• W2052768082 abstract "A small study was performed to examine whether the instillation of ricin toxoid vaccine into the lungs of Porton rats offered protection from lethal effects of subsequent intratracheal challenge with ricin toxin. Further the immune response to liposomally-encapsulated vaccine and the protection offered was compared with vaccine either adsorbed to Alhydrogel adjuvant or as a simple aqueous solution. The formaldehyde-treated ricin toxin vaccine (RTV) was administered at two dose levels, 500 and 100 micrograms kg-1 body weight to groups of rats, on two occasions by intratracheal instillation. Liposomally-encapsulated vaccine (LRTV) produced a higher titre of ricin-specific antibodies than Alhydrogel-vaccine (ARTV) and vaccine solution. When challenged with 3 LD50 of ricin by intratracheal instillation 7 weeks after the second vaccine instillation, all rats in both LRTV dose groups survived with minimal signs of incapacitation. Analysis of antibody secretion by spleen cells, 14 days post challenge, showed that the IgG isotype in the LRTV group was significantly higher than that in the ARTV and RTV groups and also that the proportion of specific IgA in lung fluid was higher in the LRTV group than in the ARTV and RTV groups. The results of this study indicate that effective vaccinations against inhaled ricin could be achieved with liposomally-encapsulated ricin toxoid, via the lung and should be investigated further." @default.
• W2052768082 created "2016-06-24" @default.
• W2052768082 creator A5006684399 @default.
• W2052768082 creator A5007173731 @default.
• W2052768082 creator A5007348853 @default.
• W2052768082 creator A5019914507 @default.
• W2052768082 creator A5031637510 @default.
• W2052768082 creator A5039568743 @default.
• W2052768082 creator A5071588466 @default.
• W2052768082 date "1997-12-01" @default.
• W2052768082 modified "2023-10-12" @default.
• W2052768082 title "Liposomally-encapsulated ricin toxoid vaccine delivered intratracheally elicits a good immune response and protects against a lethal pulmonary dose of ricin toxin" @default.
• W2052768082 cites W1013954511 @default.
• W2052768082 cites W12039071 @default.
• W2052768082 cites W1594816032 @default.
• W2052768082 cites W179940773 @default.
• W2052768082 cites W191243660 @default.
• W2052768082 cites W191756355 @default.
• W2052768082 cites W1970502718 @default.
• W2052768082 cites W1974536984 @default.
• W2052768082 cites W1974972571 @default.
• W2052768082 cites W1977437107 @default.
• W2052768082 cites W1992234269 @default.
• W2052768082 cites W1992497253 @default.
• W2052768082 cites W2009523551 @default.
• W2052768082 cites W2010543202 @default.
• W2052768082 cites W2079076826 @default.
• W2052768082 cites W2085731798 @default.
• W2052768082 cites W2088784702 @default.
• W2052768082 cites W2098021732 @default.
• W2052768082 cites W2145560663 @default.
• W2052768082 cites W2400260500 @default.
• W2052768082 cites W2406538797 @default.
• W2052768082 cites W2417835756 @default.
• W2052768082 cites W2433818723 @default.
• W2052768082 cites W37179351 @default.
• W2052768082 cites W371888784 @default.
• W2052768082 cites W41432316 @default.
• W2052768082 cites W611499483 @default.
• W2052768082 cites W645533449 @default.
• W2052768082 doi "https://doi.org/10.1016/s0264-410x(97)00123-0" @default.
• W2052768082 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9413104" @default.
• W2052768082 hasPublicationYear "1997" @default.
• W2052768082 type Work @default.
• W2052768082 sameAs 2052768082 @default.
• W2052768082 citedByCount "39" @default.
• W2052768082 countsByYear W20527680822012 @default.
• W2052768082 countsByYear W20527680822013 @default.
• W2052768082 countsByYear W20527680822014 @default.
• W2052768082 countsByYear W20527680822016 @default.
• W2052768082 countsByYear W20527680822023 @default.
• W2052768082 crossrefType "journal-article" @default.
• W2052768082 hasAuthorship W2052768082A5006684399 @default.
• W2052768082 hasAuthorship W2052768082A5007173731 @default.
• W2052768082 hasAuthorship W2052768082A5007348853 @default.
• W2052768082 hasAuthorship W2052768082A5019914507 @default.
• W2052768082 hasAuthorship W2052768082A5031637510 @default.
• W2052768082 hasAuthorship W2052768082A5039568743 @default.
• W2052768082 hasAuthorship W2052768082A5071588466 @default.
• W2052768082 hasConcept C159047783 @default.
• W2052768082 hasConcept C178790620 @default.
• W2052768082 hasConcept C185592680 @default.
• W2052768082 hasConcept C203014093 @default.
• W2052768082 hasConcept C22070199 @default.
• W2052768082 hasConcept C2777200438 @default.
• W2052768082 hasConcept C2777351567 @default.
• W2052768082 hasConcept C2777367657 @default.
• W2052768082 hasConcept C2777544843 @default.
• W2052768082 hasConcept C2777863537 @default.
• W2052768082 hasConcept C2780801004 @default.
• W2052768082 hasConcept C2780868878 @default.
• W2052768082 hasConcept C33057221 @default.
• W2052768082 hasConcept C71924100 @default.
• W2052768082 hasConcept C86803240 @default.
• W2052768082 hasConcept C8891405 @default.
• W2052768082 hasConcept C89423630 @default.
• W2052768082 hasConcept C98274493 @default.
• W2052768082 hasConceptScore W2052768082C159047783 @default.
• W2052768082 hasConceptScore W2052768082C178790620 @default.
• W2052768082 hasConceptScore W2052768082C185592680 @default.
• W2052768082 hasConceptScore W2052768082C203014093 @default.
• W2052768082 hasConceptScore W2052768082C22070199 @default.
• W2052768082 hasConceptScore W2052768082C2777200438 @default.
• W2052768082 hasConceptScore W2052768082C2777351567 @default.
• W2052768082 hasConceptScore W2052768082C2777367657 @default.
• W2052768082 hasConceptScore W2052768082C2777544843 @default.
• W2052768082 hasConceptScore W2052768082C2777863537 @default.
• W2052768082 hasConceptScore W2052768082C2780801004 @default.
• W2052768082 hasConceptScore W2052768082C2780868878 @default.
• W2052768082 hasConceptScore W2052768082C33057221 @default.
• W2052768082 hasConceptScore W2052768082C71924100 @default.
• W2052768082 hasConceptScore W2052768082C86803240 @default.
• W2052768082 hasConceptScore W2052768082C8891405 @default.
• W2052768082 hasConceptScore W2052768082C89423630 @default.
• W2052768082 hasConceptScore W2052768082C98274493 @default.
• W2052768082 hasIssue "17-18" @default.
• W2052768082 hasLocation W20527680821 @default.
• W2052768082 hasLocation W20527680822 @default.

• next