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• W2052770821 abstract "In order to evaluate the immediate effects of aortocoronary saphenous vein bypass graft surgery on myocardial contractility, studies were carried out in 24 patients with severe occlusive disease of the right or left coronary arteries or both. Myocardial contractility was expressed by the extrapolated maximal velocity of contractile elements shortening (Vmax) and peak (dP/dt)/KP (Vpm) as calculated from the left ventricular pressure and its rate of pressure rise, dP/dt by employment of a needle connected transducer. Studies were made with the patient in sinus rhythm and a stable circulation and no cardiac action drug administration before and after saphenous vein bypass surgery. The patients were divided into two groups: group 1 (12 patients) were those without LV aneurysm and satisfactory myocardial contractility (Vmax 1.40±0.07 and Vpm 1.08±0.06 muscle lengths per second), and group 2 consisted of 12 patients with poor initial myocardial contractility (Vmax±standard error 0.94±0.05 and Vpm 0.74±0.05 muscle lengths per second) and LV aneurysm. In group 1 patients there was a significant increase in Vmax and Vpm values from preoperative results (Vmax±standard error 1.84±0.09 and Vpm 1.39±0.07 muscle lengths per second (p<0.0025 and p<0.0025, respectively)). Group 2 patients did not show any significant change in Vpm values (Vpm±standard error 0.80±0.07 muscle lengths per second, p<0.35) and only a slight change in Vmax (Vmax 1.02±0.07, p<0.0125), but five out of 12 of the changes were negative (Table 5). These preliminary data indicate that increased blood supply to the myocardium delivered by aortocoronary saphenous vein bypass graft surgery is beneficial and increase myocardial contractility in those patients with good preoperative contractility. In order to evaluate the immediate effects of aortocoronary saphenous vein bypass graft surgery on myocardial contractility, studies were carried out in 24 patients with severe occlusive disease of the right or left coronary arteries or both. Myocardial contractility was expressed by the extrapolated maximal velocity of contractile elements shortening (Vmax) and peak (dP/dt)/KP (Vpm) as calculated from the left ventricular pressure and its rate of pressure rise, dP/dt by employment of a needle connected transducer. Studies were made with the patient in sinus rhythm and a stable circulation and no cardiac action drug administration before and after saphenous vein bypass surgery. The patients were divided into two groups: group 1 (12 patients) were those without LV aneurysm and satisfactory myocardial contractility (Vmax 1.40±0.07 and Vpm 1.08±0.06 muscle lengths per second), and group 2 consisted of 12 patients with poor initial myocardial contractility (Vmax±standard error 0.94±0.05 and Vpm 0.74±0.05 muscle lengths per second) and LV aneurysm. In group 1 patients there was a significant increase in Vmax and Vpm values from preoperative results (Vmax±standard error 1.84±0.09 and Vpm 1.39±0.07 muscle lengths per second (p<0.0025 and p<0.0025, respectively)). Group 2 patients did not show any significant change in Vpm values (Vpm±standard error 0.80±0.07 muscle lengths per second, p<0.35) and only a slight change in Vmax (Vmax 1.02±0.07, p<0.0125), but five out of 12 of the changes were negative (Table 5). These preliminary data indicate that increased blood supply to the myocardium delivered by aortocoronary saphenous vein bypass graft surgery is beneficial and increase myocardial contractility in those patients with good preoperative contractility." @default.
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• W2052770821 date "1974-07-01" @default.
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• W2052770821 title "Evaluation of the Immediate Effect of Aortocoronary Saphenous Vein Bypass Surgery on Myocardial Contractility" @default.
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• W2052770821 doi "https://doi.org/10.1378/chest.66.1.50" @default.
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