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- W2052803451 abstract "The synthesis of a series of non-classical bicyclic cannaboids is described.3-Phenylcyclohexanols were prepared in three steps from lithium diaryl cuprates. In preliminary tests (acetic acid-induced abdominal constriction and tail-flick tests), the compounds were found to have effective analgesic activity, comparable with δ1-tetra-hydrocannabinol. In the ring test for psychotrophic activity, the compounds exhibited no cannabis-type activity suggesting the separation of analgesic and psychotrophic activity.These compounds represent a new class of potentially potent non-opiate analgesics." @default.
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- W2052803451 date "1999-08-01" @default.
- W2052803451 modified "2023-09-23" @default.
- W2052803451 title "Synthesis and Analgesic Activity of Non-classical Bicyclic Cannabinoid Analogues" @default.
- W2052803451 doi "https://doi.org/10.1211/146080899128735234" @default.
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