FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2052806618> ?p ?o ?g. }

• W2052806618 endingPage "740" @default.
• W2052806618 startingPage "735" @default.
• W2052806618 abstract "Endothelium-derived NO is formed from L-arginine by endothelial NO synthase (eNOS) encoded by the NOS 3 gene on chromosome 7. Because several studies have indicated that NO plays a key role in the development of the atherosclerotic process, we investigated whether common variants in the eNOS gene are associated with an increased risk of plaque on carotid arteries.We studied 375 subjects attending the hypertension center of our institution to be screened for arterial hypertension. The examined subjects were classified according to the presence of carotid plaques (intima-media thickness >/=1.5 mm), and 2 intronic (CA and 27-bp repeats) polymorphisms and 1 exonic (Glu298Asp) polymorphism of the eNOS gene were explored.Only the Glu298Asp polymorphism of eNOS was associated with the presence of carotid plaques (P:<0.05). In particular, there was an excess of homozygotes for the Asp298 variant among subjects with carotid plaques, whereas the number of subjects who had the Glu298 allele in exon 7 of the eNOS gene was equally distributed in both study groups. Interestingly, the risk of having carotid plaques was increased approximately 3 times in subjects who were homozygotic for the Asp298 variant compared with subjects who were homozygotic for the Glu298 variant and was independent of the other common risk factors (age, blood pressure, and smoking).Homozygosity for Asp298, a common variant of the eNOS gene, is an independent risk factor for carotid atherosclerosis in this study population." @default.
• W2052806618 created "2016-06-24" @default.
• W2052806618 creator A5016597421 @default.
• W2052806618 creator A5027985482 @default.
• W2052806618 creator A5035713106 @default.
• W2052806618 creator A5073165523 @default.
• W2052806618 creator A5074415719 @default.
• W2052806618 creator A5074660372 @default.
• W2052806618 creator A5081441636 @default.
• W2052806618 creator A5082527578 @default.
• W2052806618 creator A5082694070 @default.
• W2052806618 creator A5085584750 @default.
• W2052806618 date "2001-03-01" @default.
• W2052806618 modified "2023-09-23" @default.
• W2052806618 title "A Common Variant of Endothelial Nitric Oxide Synthase (Glu298Asp) Is an Independent Risk Factor for Carotid Atherosclerosis" @default.
• W2052806618 cites W1974332277 @default.
• W2052806618 cites W1992040345 @default.
• W2052806618 cites W1994748801 @default.
• W2052806618 cites W1996288107 @default.
• W2052806618 cites W2028474404 @default.
• W2052806618 cites W2037656077 @default.
• W2052806618 cites W2041075406 @default.
• W2052806618 cites W2059649955 @default.
• W2052806618 cites W2066644955 @default.
• W2052806618 cites W2074759065 @default.
• W2052806618 cites W2089763926 @default.
• W2052806618 cites W2119778274 @default.
• W2052806618 cites W2127853618 @default.
• W2052806618 cites W2131868847 @default.
• W2052806618 cites W2137570167 @default.
• W2052806618 cites W2138758296 @default.
• W2052806618 cites W2313532363 @default.
• W2052806618 cites W2324841714 @default.
• W2052806618 cites W2340763215 @default.
• W2052806618 cites W2409611574 @default.
• W2052806618 cites W3022929210 @default.
• W2052806618 cites W4248289025 @default.
• W2052806618 cites W4293282543 @default.
• W2052806618 doi "https://doi.org/10.1161/01.str.32.3.735" @default.
• W2052806618 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11239195" @default.
• W2052806618 hasPublicationYear "2001" @default.
• W2052806618 type Work @default.
• W2052806618 sameAs 2052806618 @default.
• W2052806618 citedByCount "165" @default.
• W2052806618 countsByYear W20528066182012 @default.
• W2052806618 countsByYear W20528066182013 @default.
• W2052806618 countsByYear W20528066182014 @default.
• W2052806618 countsByYear W20528066182015 @default.
• W2052806618 countsByYear W20528066182016 @default.
• W2052806618 countsByYear W20528066182017 @default.
• W2052806618 countsByYear W20528066182018 @default.
• W2052806618 countsByYear W20528066182019 @default.
• W2052806618 countsByYear W20528066182020 @default.
• W2052806618 countsByYear W20528066182021 @default.
• W2052806618 countsByYear W20528066182022 @default.
• W2052806618 crossrefType "journal-article" @default.
• W2052806618 hasAuthorship W2052806618A5016597421 @default.
• W2052806618 hasAuthorship W2052806618A5027985482 @default.
• W2052806618 hasAuthorship W2052806618A5035713106 @default.
• W2052806618 hasAuthorship W2052806618A5073165523 @default.
• W2052806618 hasAuthorship W2052806618A5074415719 @default.
• W2052806618 hasAuthorship W2052806618A5074660372 @default.
• W2052806618 hasAuthorship W2052806618A5081441636 @default.
• W2052806618 hasAuthorship W2052806618A5082527578 @default.
• W2052806618 hasAuthorship W2052806618A5082694070 @default.
• W2052806618 hasAuthorship W2052806618A5085584750 @default.
• W2052806618 hasBestOaLocation W20528066181 @default.
• W2052806618 hasConcept C104317684 @default.
• W2052806618 hasConcept C126322002 @default.
• W2052806618 hasConcept C134018914 @default.
• W2052806618 hasConcept C142724271 @default.
• W2052806618 hasConcept C164705383 @default.
• W2052806618 hasConcept C180754005 @default.
• W2052806618 hasConcept C2777622882 @default.
• W2052806618 hasConcept C2778326061 @default.
• W2052806618 hasConcept C2780972559 @default.
• W2052806618 hasConcept C2908647359 @default.
• W2052806618 hasConcept C50440223 @default.
• W2052806618 hasConcept C519581460 @default.
• W2052806618 hasConcept C54355233 @default.
• W2052806618 hasConcept C71924100 @default.
• W2052806618 hasConcept C76252995 @default.
• W2052806618 hasConcept C86803240 @default.
• W2052806618 hasConcept C99454951 @default.
• W2052806618 hasConceptScore W2052806618C104317684 @default.
• W2052806618 hasConceptScore W2052806618C126322002 @default.
• W2052806618 hasConceptScore W2052806618C134018914 @default.
• W2052806618 hasConceptScore W2052806618C142724271 @default.
• W2052806618 hasConceptScore W2052806618C164705383 @default.
• W2052806618 hasConceptScore W2052806618C180754005 @default.
• W2052806618 hasConceptScore W2052806618C2777622882 @default.
• W2052806618 hasConceptScore W2052806618C2778326061 @default.
• W2052806618 hasConceptScore W2052806618C2780972559 @default.
• W2052806618 hasConceptScore W2052806618C2908647359 @default.
• W2052806618 hasConceptScore W2052806618C50440223 @default.
• W2052806618 hasConceptScore W2052806618C519581460 @default.
• W2052806618 hasConceptScore W2052806618C54355233 @default.
• W2052806618 hasConceptScore W2052806618C71924100 @default.

• next