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- W2052807537 abstract "Acid-base imbalances are an important aspect while using continuous renal replacement techniques in critically ill patients. The quality of replacement fluid needs to be considered regarding to the acid-base requirements especially in septic patients. Commonly used replacement fluids contain lactate as buffer. Whereas lactate has to enter the Cori- or Citrate-Cycle to become effective as a buffer, bicarbonate can act immediately. The metabolism of lactate in addition is depending on the impaired liver function of patients with septic shock and represents an oxygen consuming process." @default.
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- W2052807537 date "1999-01-01" @default.
- W2052807537 modified "2023-09-27" @default.
- W2052807537 title "Continuous hemodiafiltration with bicarbonate- and lactate-buffered replacement fluids in septic shock" @default.
- W2052807537 doi "https://doi.org/10.1186/cc586" @default.
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