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- W2052807913 abstract "Objectives:1) Assess the incidence of oropharyngeal squamous cell carcinoma (OPCa) in patients <45 years. 2) Assess treatments and outcomes.Methods:The SEER 9 database was queried (1973-2009) for OPCa patients <45 years of age.Results:There were 1603 patients who met the study criteria. The incidence in patients between 36-45 years increased from 0.79 to 1.39 (per 100,000). In the same time period, there was an increase in rate from 0.20 to 0.42 in whites and a decrease in rate in black patients from 0.67 to 0.32. Surgery was performed alone in 220 (13.72%) and in combination with radiation therapy in 734 (45.79%). Five-year survival for the study cohort is 54%. Compared to white patients, black patients had worse survival (P < 0.0001). Patients who had surgery as part of their treatment, either alone (localized stage patients) or in combination with radiation had the highest 5-year survival, followed by radiation.Conclusions:There was an increase in OPCa in patients within the last 4 decades, particularly in the 36-44 age range. Interestingly, the incidence increased in whites and decreased in blacks. It is important to note that the majority of these patients were treated with surgery, either alone or with radiotherapy. The rising incidence within recent decades is thought to be related to HPV transmission and changes in sexual practices." @default.
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- W2052807913 date "2013-08-23" @default.
- W2052807913 modified "2023-09-26" @default.
- W2052807913 title "Incidence and Treatment Trends in Young Patients with Oropharyngeal Cancer: The SEER Analysis" @default.
- W2052807913 doi "https://doi.org/10.1177/0194599813495815a101" @default.
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