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- W2052817512 abstract "Although the oral route is the most popular and acceptable way of drug administration owing to good patient compliance and safety, oral drug delivery is faced with continuous challenges regarding poorly soluble, poorly permeable or gastrointestinally unstable drugs such as proteins and polypeptides. The overall bioavailability and therapeutic effect still needs to be further improved by innovative delivery technologies. Recently, various novel strategies, for instance using ligand-decorated carriers, have been investigated for delivery of poorly absorptive therapeutics orally. In this review, we will discuss the state of the art of ligand-mediated targeting to intestinal epithelia for oral delivery of drugs with low bioavailability." @default.
- W2052817512 created "2016-06-24" @default.
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- W2052817512 date "2014-07-01" @default.
- W2052817512 modified "2023-10-10" @default.
- W2052817512 title "Ligand-mediated active targeting for enhanced oral absorption" @default.
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- W2052817512 doi "https://doi.org/10.1016/j.drudis.2014.03.001" @default.
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