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• W2052828260 abstract "Cinnamic acids and quinolines are known as useful scaffolds in the discovery of antitumor agents. Therefore, N-cinnamoylated analogues of chloroquine, recently reported as potent dual-action antimalarials, were evaluated against three different cancer cell lines: MKN-28, Caco-2, and MCF-7. All compounds display anti-proliferative activity in the micromolar range against the three cell lines tested, and most of them were more active than their parent drug, chloroquine, against all cell lines tested. Hence, N-cinnamoyl-chloroquine analogues are a good start towards development of affordable antitumor leads." @default.
• W2052828260 created "2016-06-24" @default.
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• W2052828260 date "2013-12-01" @default.
• W2052828260 modified "2023-09-26" @default.
• W2052828260 title "Recycling antimalarial leads for cancer: Antiproliferative properties of N-cinnamoyl chloroquine analogues" @default.
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• W2052828260 doi "https://doi.org/10.1016/j.bmcl.2013.10.025" @default.
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