Matches in SemOpenAlex for { <https://semopenalex.org/work/W2052839185> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2052839185 abstract "Background: This study monitored the prevalence and genotype distribution of HCV in patients suspected for infection as well as risk factors for infection and transmission of HCV in northeast Croatia. Methods: From January 2009 to December 2011, 405 plasma specimens of patients suspected for HCV infection were tested by the COBAS TaqMan HCV test v2.0 (Roche Diagnostics) ; 77 HCV- positive samples were genotyped using the Linear Array HCV Genotyping test (Roche) ; 33 HCV- positive patients with unfavorable liver tests were further treated with anti-viral therapy and monitored at weeks 28 and 53. Risk factors for HCV infection and transmission were analyzed from patient-filled questionnaires (age, sex, risk behavior etc.) and their clinical data (age at initial HCV infection, degree of liver inflammation and fibrosis). Results: Out of 405 tested patients, 198 (48.8%) were HCV-positive and the highest prevalence of infection was found in men and women between 30 and 40 years of age. HCV genotype distribution in northeast Croatia was similar to other European regions: G1 was the most common (66.6%), followed by G3 (22.1%), G4 (10.4%), and G2 (1.3%) ; genotypes G5 and G6 were not detected. Viral therapy evaluated at week 53 demonstrated that 58 % of patients were virus- free, 12 % had lower viral load while 12 % showed no change in viral load. Moreover, HCV G1-infected patients showed a delayed response to antiviral therapy when compared to G3 and G4-infected patients: 31 % G1-, 40 % G3- and 50 % G4-infected patients were virus-free at week 28 ; 58 % G1-, 60 % G3- and 50 % G4-infected patients were virus- free at week 53. Significant risk factors for HCV infection and transmission in northeast Croatia include history of blood transfusion, surgery before the year 1993, and body piercing in 31-40 year-old men (p<0.05). Conclusion: Our results strengthen the importance of early testing for HCV infection in men showing the symptoms of chronic hepatitis (muscle pain, appetite loss, history of jaundice) since they are statistically more often intravenous drug, piercing, and tattoo users then women in our region." @default.
- W2052839185 created "2016-06-24" @default.
- W2052839185 creator A5014366043 @default.
- W2052839185 creator A5023465249 @default.
- W2052839185 creator A5040480620 @default.
- W2052839185 creator A5061485853 @default.
- W2052839185 creator A5062612276 @default.
- W2052839185 creator A5089080025 @default.
- W2052839185 creator A5091042271 @default.
- W2052839185 creator A5091132167 @default.
- W2052839185 date "2012-06-01" @default.
- W2052839185 modified "2023-09-30" @default.
- W2052839185 title "Risk factors for Hepatitis C virus (HCV) transmission and efficiency of antiviral therapy in chronically infected patients" @default.
- W2052839185 doi "https://doi.org/10.1016/j.ijid.2012.05.175" @default.
- W2052839185 hasPublicationYear "2012" @default.
- W2052839185 type Work @default.
- W2052839185 sameAs 2052839185 @default.
- W2052839185 citedByCount "0" @default.
- W2052839185 crossrefType "journal-article" @default.
- W2052839185 hasAuthorship W2052839185A5014366043 @default.
- W2052839185 hasAuthorship W2052839185A5023465249 @default.
- W2052839185 hasAuthorship W2052839185A5040480620 @default.
- W2052839185 hasAuthorship W2052839185A5061485853 @default.
- W2052839185 hasAuthorship W2052839185A5062612276 @default.
- W2052839185 hasAuthorship W2052839185A5089080025 @default.
- W2052839185 hasAuthorship W2052839185A5091042271 @default.
- W2052839185 hasAuthorship W2052839185A5091132167 @default.
- W2052839185 hasBestOaLocation W20528391851 @default.
- W2052839185 hasConcept C104317684 @default.
- W2052839185 hasConcept C119599485 @default.
- W2052839185 hasConcept C126322002 @default.
- W2052839185 hasConcept C127413603 @default.
- W2052839185 hasConcept C135763542 @default.
- W2052839185 hasConcept C142462285 @default.
- W2052839185 hasConcept C159047783 @default.
- W2052839185 hasConcept C203014093 @default.
- W2052839185 hasConcept C2522874641 @default.
- W2052839185 hasConcept C2776408679 @default.
- W2052839185 hasConcept C2776455275 @default.
- W2052839185 hasConcept C2777510210 @default.
- W2052839185 hasConcept C2781463415 @default.
- W2052839185 hasConcept C31467283 @default.
- W2052839185 hasConcept C55493867 @default.
- W2052839185 hasConcept C71924100 @default.
- W2052839185 hasConcept C761482 @default.
- W2052839185 hasConcept C86803240 @default.
- W2052839185 hasConcept C90924648 @default.
- W2052839185 hasConceptScore W2052839185C104317684 @default.
- W2052839185 hasConceptScore W2052839185C119599485 @default.
- W2052839185 hasConceptScore W2052839185C126322002 @default.
- W2052839185 hasConceptScore W2052839185C127413603 @default.
- W2052839185 hasConceptScore W2052839185C135763542 @default.
- W2052839185 hasConceptScore W2052839185C142462285 @default.
- W2052839185 hasConceptScore W2052839185C159047783 @default.
- W2052839185 hasConceptScore W2052839185C203014093 @default.
- W2052839185 hasConceptScore W2052839185C2522874641 @default.
- W2052839185 hasConceptScore W2052839185C2776408679 @default.
- W2052839185 hasConceptScore W2052839185C2776455275 @default.
- W2052839185 hasConceptScore W2052839185C2777510210 @default.
- W2052839185 hasConceptScore W2052839185C2781463415 @default.
- W2052839185 hasConceptScore W2052839185C31467283 @default.
- W2052839185 hasConceptScore W2052839185C55493867 @default.
- W2052839185 hasConceptScore W2052839185C71924100 @default.
- W2052839185 hasConceptScore W2052839185C761482 @default.
- W2052839185 hasConceptScore W2052839185C86803240 @default.
- W2052839185 hasConceptScore W2052839185C90924648 @default.
- W2052839185 hasLocation W20528391851 @default.
- W2052839185 hasOpenAccess W2052839185 @default.
- W2052839185 hasPrimaryLocation W20528391851 @default.
- W2052839185 hasRelatedWork W1496400210 @default.
- W2052839185 hasRelatedWork W1560905160 @default.
- W2052839185 hasRelatedWork W178836117 @default.
- W2052839185 hasRelatedWork W1937172910 @default.
- W2052839185 hasRelatedWork W2108521380 @default.
- W2052839185 hasRelatedWork W2149731190 @default.
- W2052839185 hasRelatedWork W2163832168 @default.
- W2052839185 hasRelatedWork W2167732536 @default.
- W2052839185 hasRelatedWork W2246787776 @default.
- W2052839185 hasRelatedWork W2355886178 @default.
- W2052839185 hasRelatedWork W2387472212 @default.
- W2052839185 hasRelatedWork W2406767238 @default.
- W2052839185 hasRelatedWork W2409887450 @default.
- W2052839185 hasRelatedWork W2418153461 @default.
- W2052839185 hasRelatedWork W2495482650 @default.
- W2052839185 hasRelatedWork W2790468436 @default.
- W2052839185 hasRelatedWork W2971070407 @default.
- W2052839185 hasRelatedWork W3093976272 @default.
- W2052839185 hasRelatedWork W3192385798 @default.
- W2052839185 hasRelatedWork W2316652110 @default.
- W2052839185 isParatext "false" @default.
- W2052839185 isRetracted "false" @default.
- W2052839185 magId "2052839185" @default.
- W2052839185 workType "article" @default.