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- W2052869477 abstract "Following acute intracerebroventricular injections of 1 ng of apamin and chronic apamin infusion (0.4 ng/μl, 0.5 μl/h, 14 days), the rat brains exhibited bilateral damage only in the cerebellum. The argyrophilic cells were Purkinje cells in copula pyramis, flocculus, paraflocculus, and paramedian lobules. These data demonstrate that the inactivation of small conductance Ca2+-activated K+ channels by apamin induces a non-limbic neurodegeneration." @default.
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- W2052869477 date "1997-12-01" @default.
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- W2052869477 title "Apamin, a blocker of the calcium-activated potassium channel, induces neurodegeneration of Purkinje cells exclusively" @default.
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- W2052869477 doi "https://doi.org/10.1016/s0006-8993(97)01165-7" @default.
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