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- W2052912105 abstract "Intraperitoneal injection of glucose was found to cause a dose and time dependent suppression of superoxide dismutase activity in mouse heart. Manganese superoxide dismutase was more sensitive to glucose suppression than Cu-Zn superoxide dismutase. While glucose suppressed the Mn form of the enzyme at the concentration of 1.5 mg/kg, it did not have a significant effect on Cu-Zn superoxide dismutase activity at this concentration. The maximum suppression for both forms of superoxide dismutase activity occurred at 4.5 mg/kg. Glucose also suppressed manganese superoxide dismutase activity in mouse heart for a longer period of time compared to Cu-Zn superoxide dismutase. Glucose suppression also occurred in mouse brain. The glucose suppression effect on manganese superoxide dismutase activity in the heart was partially alleviated by X-irradiation." @default.
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- W2052912105 date "1984-07-01" @default.
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- W2052912105 title "Regulation of Mn-SOD activity in the mouse heart: Glucose effect" @default.
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- W2052912105 doi "https://doi.org/10.1016/s0006-291x(84)80087-x" @default.
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