Matches in SemOpenAlex for { <https://semopenalex.org/work/W2052916852> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2052916852 endingPage "6771" @default.
- W2052916852 startingPage "6767" @default.
- W2052916852 abstract "The catalytic subunit of the H+/K(+)-transporting ATPase (EC 3.6.1.3) has 62% identity to the alpha, or catalytic subunit, of the Na+/K(+)-transporting ATPase (EC 3.6.1.37); however, a homologous beta subunit was unknown until recently. Removal of the carbohydrate from purified hog H+/K(+)ATPase vesicles reveals a 35-kDa peptide that, when fragmented with protease V8, gives sequences homologous to both beta 1 and beta 2 subunits of the Na+/K(+)-ATPase. cDNA clones for a beta subunit of the gastric H+/K(+)-ATPase were isolated from a rabbit stomach cDNA library by using degenerate 17-mer oligonucleotide probes made to the protease V8-treated peptides. An open reading frame (54-926) encodes a predicted 291-amino acid peptide with Mr = 33,320, which exhibits 31% and 44% homologies to the Na+/K+)-ATPase beta 1 and Na+/K(+)-ATPase beta 2 proteins, respectively. A Kyte-Doolittle hydropathy plot predicts a single N-terminal transmembrane domain with a small hydrophobic region near the C terminus. The presumed extracytosolic domain contains seven potential N-linked glycosylation sites and six out of nine cysteines. Northern (RNA) blot analysis of stomach RNA with the rabbit H+/K(+)-ATPase beta probe identifies a single mRNA of 1.3-1.5 kilobases, similar in concentration to the alpha subunit mRNA. The presence of a defined gastric H+/K(+)-ATPase beta subunit extends the homology between H+/K(+)-ATPase and the Na+/K(+)-ATPase subclass of phosphoenzyme transport ATPases and distinguishes them from the monomeric Ca2+ and proton pump subclasses." @default.
- W2052916852 created "2016-06-24" @default.
- W2052916852 creator A5057185561 @default.
- W2052916852 creator A5075847202 @default.
- W2052916852 creator A5084830770 @default.
- W2052916852 date "1990-09-01" @default.
- W2052916852 modified "2023-10-18" @default.
- W2052916852 title "Characterization of a beta subunit of the gastric H+/K(+)-transporting ATPase." @default.
- W2052916852 cites W1537460308 @default.
- W2052916852 cites W1573051141 @default.
- W2052916852 cites W1578508637 @default.
- W2052916852 cites W1860160290 @default.
- W2052916852 cites W1990205754 @default.
- W2052916852 cites W2002739607 @default.
- W2052916852 cites W2009310436 @default.
- W2052916852 cites W2032413102 @default.
- W2052916852 cites W2051313211 @default.
- W2052916852 cites W2058844233 @default.
- W2052916852 cites W2061987647 @default.
- W2052916852 cites W2062801478 @default.
- W2052916852 cites W2078444745 @default.
- W2052916852 cites W2110565876 @default.
- W2052916852 cites W2125040075 @default.
- W2052916852 cites W2138270253 @default.
- W2052916852 cites W2154128645 @default.
- W2052916852 cites W2443284080 @default.
- W2052916852 cites W64648999 @default.
- W2052916852 doi "https://doi.org/10.1073/pnas.87.17.6767" @default.
- W2052916852 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/54618" @default.
- W2052916852 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2168558" @default.
- W2052916852 hasPublicationYear "1990" @default.
- W2052916852 type Work @default.
- W2052916852 sameAs 2052916852 @default.
- W2052916852 citedByCount "133" @default.
- W2052916852 countsByYear W20529168522012 @default.
- W2052916852 countsByYear W20529168522013 @default.
- W2052916852 countsByYear W20529168522016 @default.
- W2052916852 countsByYear W20529168522019 @default.
- W2052916852 countsByYear W20529168522020 @default.
- W2052916852 countsByYear W20529168522022 @default.
- W2052916852 crossrefType "journal-article" @default.
- W2052916852 hasAuthorship W2052916852A5057185561 @default.
- W2052916852 hasAuthorship W2052916852A5075847202 @default.
- W2052916852 hasAuthorship W2052916852A5084830770 @default.
- W2052916852 hasBestOaLocation W20529168522 @default.
- W2052916852 hasConcept C104292427 @default.
- W2052916852 hasConcept C104317684 @default.
- W2052916852 hasConcept C118892022 @default.
- W2052916852 hasConcept C153911025 @default.
- W2052916852 hasConcept C167625842 @default.
- W2052916852 hasConcept C181199279 @default.
- W2052916852 hasConcept C187882448 @default.
- W2052916852 hasConcept C23265538 @default.
- W2052916852 hasConcept C2911069308 @default.
- W2052916852 hasConcept C515207424 @default.
- W2052916852 hasConcept C55493867 @default.
- W2052916852 hasConcept C83730767 @default.
- W2052916852 hasConcept C86803240 @default.
- W2052916852 hasConceptScore W2052916852C104292427 @default.
- W2052916852 hasConceptScore W2052916852C104317684 @default.
- W2052916852 hasConceptScore W2052916852C118892022 @default.
- W2052916852 hasConceptScore W2052916852C153911025 @default.
- W2052916852 hasConceptScore W2052916852C167625842 @default.
- W2052916852 hasConceptScore W2052916852C181199279 @default.
- W2052916852 hasConceptScore W2052916852C187882448 @default.
- W2052916852 hasConceptScore W2052916852C23265538 @default.
- W2052916852 hasConceptScore W2052916852C2911069308 @default.
- W2052916852 hasConceptScore W2052916852C515207424 @default.
- W2052916852 hasConceptScore W2052916852C55493867 @default.
- W2052916852 hasConceptScore W2052916852C83730767 @default.
- W2052916852 hasConceptScore W2052916852C86803240 @default.
- W2052916852 hasIssue "17" @default.
- W2052916852 hasLocation W20529168521 @default.
- W2052916852 hasLocation W20529168522 @default.
- W2052916852 hasLocation W20529168523 @default.
- W2052916852 hasLocation W20529168524 @default.
- W2052916852 hasOpenAccess W2052916852 @default.
- W2052916852 hasPrimaryLocation W20529168521 @default.
- W2052916852 hasRelatedWork W1978515640 @default.
- W2052916852 hasRelatedWork W1980622692 @default.
- W2052916852 hasRelatedWork W2003360892 @default.
- W2052916852 hasRelatedWork W2064020921 @default.
- W2052916852 hasRelatedWork W2072833094 @default.
- W2052916852 hasRelatedWork W2084810014 @default.
- W2052916852 hasRelatedWork W2092603638 @default.
- W2052916852 hasRelatedWork W2460547791 @default.
- W2052916852 hasRelatedWork W2912072342 @default.
- W2052916852 hasRelatedWork W4248293825 @default.
- W2052916852 hasVolume "87" @default.
- W2052916852 isParatext "false" @default.
- W2052916852 isRetracted "false" @default.
- W2052916852 magId "2052916852" @default.
- W2052916852 workType "article" @default.