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- W2052930769 abstract "Abstract The discovery of resmethrin almost five decades ago was the seminal event in the development of pyrethroid insecticides as important pest management tools, the value of which endures to this day. This brief review considers the development of pyrethroids from the perspective of the discovery of resmethrin. I describe the pathway to the discovery of resmethrin and the unique properties that differentiated it from the pyrethrins and earlier synthetic pyrethroids is described. I also summarize information on metabolic fate and mechanisms of selective toxicity, first elucidated with resmethrin, that have shaped our understanding of pyrethroid toxicology since that time. Finally, I review the discovery pathway that led from resmethrin to the development of the first photostable, agriculturally useful pyrethroids that established the importance of this insecticide class. © 2014 Society of Chemical Industry" @default.
- W2052930769 created "2016-06-24" @default.
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- W2052930769 date "2014-11-17" @default.
- W2052930769 modified "2023-09-25" @default.
- W2052930769 title "Resmethrin, the first modern pyrethroid insecticide" @default.
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- W2052930769 doi "https://doi.org/10.1002/ps.3881" @default.
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