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- W2052979314 abstract "Previous reports have suggested that estrogen is involved in bivalve reproduction and have also hypothesized that its effects are mediated through binding sites on specific receptors. In this study, we provide initial characterization of the estrogen binding sites in the gonads of both female and male sea scallops (Placopecten magellanicus). Saturation analyses indicated two binding sites in fractions which have classically been used to represent the cytosol and the nucleus. One binding site is characterized by high affinity and limited binding capacity while the other site is characterized by low affinity and high capacity. Competitive binding analyses demonstrated that these sites can bind natural and synthetic estrogens with high affinity but only bind testosterone and progesterone at high concentrations. Comparison of binding capacity in scallops at different sexual maturation stages suggested that these sites may be involved in reproductive regulation in sea scallops." @default.
- W2052979314 created "2016-06-24" @default.
- W2052979314 creator A5014827585 @default.
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- W2052979314 date "2007-11-01" @default.
- W2052979314 modified "2023-09-27" @default.
- W2052979314 title "Estrogen binding sites in the sea scallop: Characterization and possible involvement in reproductive regulation" @default.
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- W2052979314 doi "https://doi.org/10.1016/j.cbpb.2007.06.008" @default.
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