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- W205300518 abstract "This chapter presents an analysis of antigenic structure of Clostridium botulinum type C1 and D toxins by monoclonal antibodies. Clostridium botulinum produces one of the most powerful neuroparalytic poisons that affect a great variety of animal species in all parts of the world. Clostridium botulinum cultures can be divided into four groups: (1) proteolytic, which produce toxin types A, B, or F; (2) non-proteolytic, which produce toxin types B, E, or F; (3) type Cα, Cβ, and D cultures; and (4) proteolytic but non-saccharolytic type G. Hybridomas producing antibodies to toxins are screened by enzyme-linked immunosorbent assay. The production of a major toxin in certain type C and D cultures is governed by specific bacteriophages. Curing these cultures of their prophages results in concomitant loss of the dominant toxin production, and the non-toxigenic cultures are reconverted to toxin producers by the infection with phages." @default.
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- W205300518 date "1985-01-01" @default.
- W205300518 modified "2023-09-26" @default.
- W205300518 title "Analysis of Antigenic Structure of Clostridium botulinum Type C1 and D Toxins by Monoclonal Antibodies" @default.
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- W205300518 doi "https://doi.org/10.1016/b978-0-12-463002-4.50015-x" @default.
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