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• W2053006593 abstract "The effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) on the interaction between the fungus Torulopsis glabrata and human neutrophils was examined. Pre-incubation of neutrophils with GM-CSF increased the neutrophil fungal killing. The cytokine also increased the oxygen-dependent respiratory burst in response to opsonized fungi, measured by the lucigenin-dependent chemiluminescence assay and superoxide release. Under the same conditions the cytokine augmented release of constituents from both specific and azurophilic granules. Besides these priming effects, GM-CSF was a weak stimulus of the neutrophil respiratory burst and degranulation. The priming and stimulatory effects of GM-CSF were observed at 10-1000 U/ml with an optimal concentration of 100 U/ml." @default.
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• W2053006593 date "2008-06-28" @default.
• W2053006593 modified "2023-09-25" @default.
• W2053006593 title "Granulocyte-macrophage colony-stimulating factor augments neutrophil killing of Torulopsis glabrata and stimulates neutrophil respiratory burst and degranulation" @default.
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• W2053006593 doi "https://doi.org/10.1111/j.1365-2249.1991.tb05619.x" @default.
• W2053006593 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1535258" @default.
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