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- W2053006875 abstract "Ultraviolet absorption data and thermal chromatography through hydroxyapatite (HAP) column revealed that furazolidone treatment of Vibrio cholerae cells produced more than 80% of DNA reversibly bihelical due to the formation of interstrand cross-links and the reaction obeyed a first order relation. Sensitivities of the Escherichia coli strains to the lethal action of the drug were in the order: AB 2480(uvr−rec−) > AB 2463(rec−) > AB 1886(uvr−) > AB 1157(repair proficient) or AB 4401(wild type). Furazolidone was ‘Rec test’ positive, produced dose-dependent prophage induction in E. coli cells and also dose-dependent streptomycin-resistance forward mutation in V. cholerae cells. The quantitative aspect and also the mode of furazolidone action on DNA were discussed." @default.
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- W2053006875 date "1983-08-01" @default.
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- W2053006875 title "DNA damage, prophage induction and mutation by furazolidone" @default.
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- W2053006875 doi "https://doi.org/10.1016/0009-2797(83)90078-9" @default.
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