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- W2053009898 abstract "We describe an efficient solid-phase synthesis of clavulones via the sequential coupling of the α- and ω-chains, involving two separate carbon−carbon bond-forming steps. The tetrahydropyranyl linker survived these reaction conditions and was cleaved without decomposing the unstable cross-conjugated dienones. Our methodology has allowed us to prepare six clavulone derivatives that are varied within the α-chain." @default.
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- W2053009898 date "2004-03-09" @default.
- W2053009898 modified "2023-09-24" @default.
- W2053009898 title "Efficient Solid-Phase Synthesis of Clavulones via Sequential Coupling of α- and ω-Chains" @default.
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- W2053009898 doi "https://doi.org/10.1021/ol036361b" @default.
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