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- W2053016831 abstract "Current perspectives on empirical, modeling, and mechanistic methods of medical device safety testing are reviewed. Empirical approaches, such as the U.S. Pharmacopeial biological tests for plastics, evaluate the total system to discover aberrations and abnormalities. Models consist of a single aspect of an integrated approach, whereas mechanistic methods are based on a thorough knowledge of the materials and the organism's biological response. Empirical studies develop data on general hazard potential, such as overt toxicity. Model approaches target the specific application and specific hazard potential. Mechanistic studies identify the cause of toxicity and can produce advances in the biocompatibility of medical devices." @default.
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- W2053016831 date "1987-01-01" @default.
- W2053016831 modified "2023-09-27" @default.
- W2053016831 title "Strategies for Biological Testing of Biomaterials" @default.
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- W2053016831 doi "https://doi.org/10.1177/088532828700200104" @default.
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