Matches in SemOpenAlex for { <https://semopenalex.org/work/W2053031401> ?p ?o ?g. }
- W2053031401 endingPage "4123" @default.
- W2053031401 startingPage "4118" @default.
- W2053031401 abstract "Whereas many physicochemical investigations have shown that among monovalent cations Na+ ion possesses minimal potential for DNA binding, biological assays have shown that Na+ ion (in contrast to K+ ion) plays a primary role in chromatin compaction and related processes. It is difficult to explain this inverse relationship between the compaction potentials of Na+ and K+ and their binding abilities. In this study we sought to resolve this contradiction and emphasize the phenomenological distinction between DNA compaction and DNA binding processes in the case of DNA compaction by monocations. Using polyethylene glycol solutions as a model of a crowded cell environment, we studied DNA compaction by alkali metal salts LiCl, NaCl, KCl, RbCl, and CsCl, and found that all of these monocations promote DNA compaction. Among these monovalent cations Na+ produces the greatest compaction and the ratio of K+ cand Na+ oncentrations for DNA compaction is ∼1.5–2. A comparative analysis of recent experimental results indicates that a higher binding activity of monocation generally corresponds to a low compaction potential of the corresponding monovalent ion. This inverse relation is explained as a result of partial dehydration of monocations in the compact state." @default.
- W2053031401 created "2016-06-24" @default.
- W2053031401 creator A5001597356 @default.
- W2053031401 creator A5010168885 @default.
- W2053031401 date "2005-06-01" @default.
- W2053031401 modified "2023-10-16" @default.
- W2053031401 title "Na+ Shows a Markedly Higher Potential than K+ in DNA Compaction in a Crowded Environment" @default.
- W2053031401 cites W1545223406 @default.
- W2053031401 cites W160102508 @default.
- W2053031401 cites W1963798828 @default.
- W2053031401 cites W1968463331 @default.
- W2053031401 cites W1972832968 @default.
- W2053031401 cites W1976462848 @default.
- W2053031401 cites W1978477681 @default.
- W2053031401 cites W1983758346 @default.
- W2053031401 cites W1991334160 @default.
- W2053031401 cites W1995241314 @default.
- W2053031401 cites W1998904980 @default.
- W2053031401 cites W2004388607 @default.
- W2053031401 cites W2014767474 @default.
- W2053031401 cites W2020165516 @default.
- W2053031401 cites W2029428403 @default.
- W2053031401 cites W2032786397 @default.
- W2053031401 cites W2039792018 @default.
- W2053031401 cites W2048472020 @default.
- W2053031401 cites W2056144602 @default.
- W2053031401 cites W2059720471 @default.
- W2053031401 cites W2059992766 @default.
- W2053031401 cites W2060475454 @default.
- W2053031401 cites W2067229943 @default.
- W2053031401 cites W2070340316 @default.
- W2053031401 cites W2078562773 @default.
- W2053031401 cites W2078919764 @default.
- W2053031401 cites W2084250387 @default.
- W2053031401 cites W2113476494 @default.
- W2053031401 cites W2116119592 @default.
- W2053031401 cites W2129161705 @default.
- W2053031401 cites W2141778672 @default.
- W2053031401 cites W2150303730 @default.
- W2053031401 cites W2154322715 @default.
- W2053031401 cites W2187377291 @default.
- W2053031401 doi "https://doi.org/10.1529/biophysj.104.057323" @default.
- W2053031401 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1305642" @default.
- W2053031401 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15778438" @default.
- W2053031401 hasPublicationYear "2005" @default.
- W2053031401 type Work @default.
- W2053031401 sameAs 2053031401 @default.
- W2053031401 citedByCount "86" @default.
- W2053031401 countsByYear W20530314012012 @default.
- W2053031401 countsByYear W20530314012013 @default.
- W2053031401 countsByYear W20530314012014 @default.
- W2053031401 countsByYear W20530314012015 @default.
- W2053031401 countsByYear W20530314012016 @default.
- W2053031401 countsByYear W20530314012017 @default.
- W2053031401 countsByYear W20530314012018 @default.
- W2053031401 countsByYear W20530314012019 @default.
- W2053031401 countsByYear W20530314012020 @default.
- W2053031401 countsByYear W20530314012021 @default.
- W2053031401 countsByYear W20530314012022 @default.
- W2053031401 countsByYear W20530314012023 @default.
- W2053031401 crossrefType "journal-article" @default.
- W2053031401 hasAuthorship W2053031401A5001597356 @default.
- W2053031401 hasAuthorship W2053031401A5010168885 @default.
- W2053031401 hasBestOaLocation W20530314011 @default.
- W2053031401 hasConcept C12554922 @default.
- W2053031401 hasConcept C145148216 @default.
- W2053031401 hasConcept C159985019 @default.
- W2053031401 hasConcept C178790620 @default.
- W2053031401 hasConcept C185592680 @default.
- W2053031401 hasConcept C192562407 @default.
- W2053031401 hasConcept C196715460 @default.
- W2053031401 hasConcept C198091228 @default.
- W2053031401 hasConcept C552990157 @default.
- W2053031401 hasConcept C55493867 @default.
- W2053031401 hasConcept C83640560 @default.
- W2053031401 hasConcept C86803240 @default.
- W2053031401 hasConceptScore W2053031401C12554922 @default.
- W2053031401 hasConceptScore W2053031401C145148216 @default.
- W2053031401 hasConceptScore W2053031401C159985019 @default.
- W2053031401 hasConceptScore W2053031401C178790620 @default.
- W2053031401 hasConceptScore W2053031401C185592680 @default.
- W2053031401 hasConceptScore W2053031401C192562407 @default.
- W2053031401 hasConceptScore W2053031401C196715460 @default.
- W2053031401 hasConceptScore W2053031401C198091228 @default.
- W2053031401 hasConceptScore W2053031401C552990157 @default.
- W2053031401 hasConceptScore W2053031401C55493867 @default.
- W2053031401 hasConceptScore W2053031401C83640560 @default.
- W2053031401 hasConceptScore W2053031401C86803240 @default.
- W2053031401 hasIssue "6" @default.
- W2053031401 hasLocation W20530314011 @default.
- W2053031401 hasLocation W20530314012 @default.
- W2053031401 hasLocation W20530314013 @default.
- W2053031401 hasLocation W20530314014 @default.
- W2053031401 hasOpenAccess W2053031401 @default.
- W2053031401 hasPrimaryLocation W20530314011 @default.
- W2053031401 hasRelatedWork W2004528270 @default.
- W2053031401 hasRelatedWork W2028550458 @default.
- W2053031401 hasRelatedWork W2087846525 @default.