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- W2053035653 abstract "Background: Multiple myeloma (MM) itself is not considered to be responsible for fever and is not usually listed among the causes of fever of unknown origin (FUO). Methods: We report three cases of MM presenting with specific fever that we analyze in combination with the three previously published cases. Results: MM could easily be suspected in most, but not all, cases, emphasizing that bone marrow aspiration should be a part of ‘standard’ FUO investigations. All patients underwent extensive, sometimes potentially harmful, investigations. Conventional treatment of MM produced a sustained improvement in the temperature curve and inflammatory syndrome in all cases within a few months. Fever recurred during nearly all relapses. Six patients died, one after a disease course of more than 8 years. Conclusions: This series shows that MM may present as a FUO and that useless and hazardous investigations may be avoided given the possibility of specific fever in this disease. Chemotherapy must be considered without much delay after a reasonable work-up to eliminate any associated process, especially infections." @default.
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- W2053035653 date "2003-03-01" @default.
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- W2053035653 title "Multiple myeloma presenting as fever of unknown origin" @default.
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- W2053035653 doi "https://doi.org/10.1016/s0953-6205(03)00021-9" @default.
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