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- W2053202301 abstract "cDNA clones encoding rodent IgE-binding factors (IgE-BF) were isolated from cDNA libraries of a rat-mouse T hybridoma that secretes IgE-suppressive factor (IgE-SF) upon incubation with rat IgE. COS7 cells transfected with two of the cDNAs expressed IgE-BF, which selectively potentiate an in vitro IgE response. IgE-BF expressed in COS7 cells are glycoproteins of approximately equal to 60 and approximately equal to 11 kDa. DNA sequence analysis of an IgE-BF cDNA revealed a 556-amino acid (62 kDa) protein coding region. The results suggest that IgE-potentiating and IgE-suppressive factors share common precursor polypeptides and that the 11-kDa IgE-BF is derived from a 60-kDa precursor." @default.
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- W2053202301 date "1985-04-01" @default.
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- W2053202301 title "cDNA clones encoding IgE-binding factors from a rat-mouse T-cell hybridoma." @default.
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- W2053202301 doi "https://doi.org/10.1073/pnas.82.8.2460" @default.
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