FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2053207892> ?p ?o ?g. }

• W2053207892 endingPage "488" @default.
• W2053207892 startingPage "484" @default.
• W2053207892 abstract "The antirejection drug tacrolimus (FK506) has been reported to impair intestinal permeability in an early stage after orthotopic liver transplantation (OLT), and cyclosporine (CsA) has shown a similar effect in animals. We studied the chronic effect of FK506 and CsA on gastroduodenal and intestinal permeability and on blood endotoxin levels in patients 2 to 3 years after OLT. Thirty-two OLT patients (22 men and 10 women; mean age, 44.8 ± 7.1) who had received CsA (n = 19) or FK506 (n = 13) and 10 healthy volunteers (6 male and 4 female, mean age 41.7 ± 5.4) were assessed for gastroduodenal permeability by recovery in urine of sucrose after oral administration and for intestinal permeability by recovery in urine after oral loads of rhamnose and lactulose, which evaluate the intracellular and paracellular routes, respectively. In all subjects, plasma levels of endotoxins also were assessed. Gastroduodenal permeability was similar in patients and controls (0.03 ± 0.003 versus 0.04 ± 0.01%, P = NS). In regard to intestinal permeability, passage through the intracellular route was significantly reduced in OLT patients compared with controls (1.13 ± 0.06 versus 2.74 ± 0.17%, P < .01), but paracellular permeability was unchanged (0.14 ± 0.007 versus 0.13 ± 0.01%, P = NS). Serum endotoxin levels were similar in all subjects. We conclude that chronic administration of FK506 or CsA induces a clinically irrelevant, selective dysfunction of monosaccharide absorption, but does not affect gastroduodenal or intestinal permeability." @default.
• W2053207892 created "2016-06-24" @default.
• W2053207892 creator A5014566953 @default.
• W2053207892 creator A5015482109 @default.
• W2053207892 creator A5019938964 @default.
• W2053207892 creator A5029189045 @default.
• W2053207892 creator A5031998312 @default.
• W2053207892 creator A5044401500 @default.
• W2053207892 creator A5056403286 @default.
• W2053207892 creator A5076382407 @default.
• W2053207892 date "2003-05-01" @default.
• W2053207892 modified "2023-10-14" @default.
• W2053207892 title "Effect of chronic administration of tacrolimus and cyclosporine on human gastrointestinal permeability" @default.
• W2053207892 cites W1618156669 @default.
• W2053207892 cites W1979491478 @default.
• W2053207892 cites W1989356686 @default.
• W2053207892 cites W2002297392 @default.
• W2053207892 cites W2003661505 @default.
• W2053207892 cites W2012007137 @default.
• W2053207892 cites W2022975557 @default.
• W2053207892 cites W2026549297 @default.
• W2053207892 cites W2036599441 @default.
• W2053207892 cites W2051127053 @default.
• W2053207892 cites W2052147433 @default.
• W2053207892 cites W2063393472 @default.
• W2053207892 cites W2073308995 @default.
• W2053207892 cites W2076268703 @default.
• W2053207892 cites W2100200241 @default.
• W2053207892 cites W2108759049 @default.
• W2053207892 cites W2112146497 @default.
• W2053207892 cites W2123170641 @default.
• W2053207892 cites W2171516474 @default.
• W2053207892 cites W4230154854 @default.
• W2053207892 cites W4252770165 @default.
• W2053207892 cites W44457639 @default.
• W2053207892 cites W72541202 @default.
• W2053207892 doi "https://doi.org/10.1053/jlts.2003.50088" @default.
• W2053207892 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12740791" @default.
• W2053207892 hasPublicationYear "2003" @default.
• W2053207892 type Work @default.
• W2053207892 sameAs 2053207892 @default.
• W2053207892 citedByCount "19" @default.
• W2053207892 countsByYear W20532078922013 @default.
• W2053207892 countsByYear W20532078922015 @default.
• W2053207892 countsByYear W20532078922016 @default.
• W2053207892 countsByYear W20532078922017 @default.
• W2053207892 countsByYear W20532078922018 @default.
• W2053207892 countsByYear W20532078922019 @default.
• W2053207892 countsByYear W20532078922020 @default.
• W2053207892 countsByYear W20532078922021 @default.
• W2053207892 countsByYear W20532078922022 @default.
• W2053207892 countsByYear W20532078922023 @default.
• W2053207892 crossrefType "journal-article" @default.
• W2053207892 hasAuthorship W2053207892A5014566953 @default.
• W2053207892 hasAuthorship W2053207892A5015482109 @default.
• W2053207892 hasAuthorship W2053207892A5019938964 @default.
• W2053207892 hasAuthorship W2053207892A5029189045 @default.
• W2053207892 hasAuthorship W2053207892A5031998312 @default.
• W2053207892 hasAuthorship W2053207892A5044401500 @default.
• W2053207892 hasAuthorship W2053207892A5056403286 @default.
• W2053207892 hasAuthorship W2053207892A5076382407 @default.
• W2053207892 hasBestOaLocation W20532078921 @default.
• W2053207892 hasConcept C120882062 @default.
• W2053207892 hasConcept C126322002 @default.
• W2053207892 hasConcept C134018914 @default.
• W2053207892 hasConcept C2777056448 @default.
• W2053207892 hasConcept C2777448540 @default.
• W2053207892 hasConcept C2781071285 @default.
• W2053207892 hasConcept C2909675724 @default.
• W2053207892 hasConcept C2911091166 @default.
• W2053207892 hasConcept C41625074 @default.
• W2053207892 hasConcept C54355233 @default.
• W2053207892 hasConcept C60903277 @default.
• W2053207892 hasConcept C71924100 @default.
• W2053207892 hasConcept C86803240 @default.
• W2053207892 hasConcept C90924648 @default.
• W2053207892 hasConcept C98274493 @default.
• W2053207892 hasConceptScore W2053207892C120882062 @default.
• W2053207892 hasConceptScore W2053207892C126322002 @default.
• W2053207892 hasConceptScore W2053207892C134018914 @default.
• W2053207892 hasConceptScore W2053207892C2777056448 @default.
• W2053207892 hasConceptScore W2053207892C2777448540 @default.
• W2053207892 hasConceptScore W2053207892C2781071285 @default.
• W2053207892 hasConceptScore W2053207892C2909675724 @default.
• W2053207892 hasConceptScore W2053207892C2911091166 @default.
• W2053207892 hasConceptScore W2053207892C41625074 @default.
• W2053207892 hasConceptScore W2053207892C54355233 @default.
• W2053207892 hasConceptScore W2053207892C60903277 @default.
• W2053207892 hasConceptScore W2053207892C71924100 @default.
• W2053207892 hasConceptScore W2053207892C86803240 @default.
• W2053207892 hasConceptScore W2053207892C90924648 @default.
• W2053207892 hasConceptScore W2053207892C98274493 @default.
• W2053207892 hasIssue "5" @default.
• W2053207892 hasLocation W20532078921 @default.
• W2053207892 hasLocation W20532078922 @default.
• W2053207892 hasOpenAccess W2053207892 @default.
• W2053207892 hasPrimaryLocation W20532078921 @default.
• W2053207892 hasRelatedWork W129336396 @default.

• next