FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2053233405> ?p ?o ?g. }

• W2053233405 endingPage "389" @default.
• W2053233405 startingPage "381" @default.
• W2053233405 abstract "<i>Background:</i> Diabetic nephropathy (DN) is a leading cause of mortality and morbidity in patients with type 1 and type 2 diabetes. The multicenter FIND consortium aims to identify genes for DN and its associated quantitative traits, e.g. the urine albumin:creatinine ratio (ACR). Herein, the results of whole-genome linkage analysis and a sparse association scan for ACR and a dichotomous DN phenotype are reported in diabetic individuals. <i>Methods:</i> A genomewide scan comprising more than 5,500 autosomal single nucleotide polymorphism markers (average spacing of 0.6 cM) was performed on 1,235 nuclear and extended pedigrees (3,972 diabetic participants) ascertained for DN from African-American (AA), American-Indian (AI), European-American (EA) and Mexican-American (MA) populations. <i>Results:</i> Strong evidence for linkage to DN was detected on chromosome 6p (p = 8.0 × 10^–5, LOD = 3.09) in EA families as well as suggestive evidence for linkage to chromosome 7p in AI families. Regions on chromosomes 3p in AA, 7q in EA, 16q in AA and 22q in MA displayed suggestive evidence of linkage for urine ACR. The linkage peak on chromosome 22q overlaps the <i>MYH9/APOL1</i> gene region, previously implicated in AA diabetic and nondiabetic nephropathies. <i>Conclusion:</i> These results strengthen the evidence for previously identified genomic regions and implicate several novel loci potentially involved in the pathogenesis of DN." @default.
• W2053233405 created "2016-06-24" @default.
• W2053233405 creator A5002770996 @default.
• W2053233405 creator A5004754655 @default.
• W2053233405 creator A5005079192 @default.
• W2053233405 creator A5008471831 @default.
• W2053233405 creator A5009102261 @default.
• W2053233405 creator A5017342914 @default.
• W2053233405 creator A5017453385 @default.
• W2053233405 creator A5024733766 @default.
• W2053233405 creator A5030650722 @default.
• W2053233405 creator A5031109876 @default.
• W2053233405 creator A5034748018 @default.
• W2053233405 creator A5037848101 @default.
• W2053233405 creator A5041935551 @default.
• W2053233405 creator A5042371019 @default.
• W2053233405 creator A5049047999 @default.
• W2053233405 creator A5050165878 @default.
• W2053233405 creator A5055517777 @default.
• W2053233405 creator A5058056616 @default.
• W2053233405 creator A5058716877 @default.
• W2053233405 creator A5058772970 @default.
• W2053233405 creator A5059128990 @default.
• W2053233405 creator A5059764563 @default.
• W2053233405 creator A5059771971 @default.
• W2053233405 creator A5069385226 @default.
• W2053233405 creator A5071417113 @default.
• W2053233405 creator A5073806384 @default.
• W2053233405 creator A5075115334 @default.
• W2053233405 creator A5079294410 @default.
• W2053233405 creator A5087036525 @default.
• W2053233405 creator A5087955884 @default.
• W2053233405 creator A5088560891 @default.
• W2053233405 creator A5090013988 @default.
• W2053233405 date "2011-01-01" @default.
• W2053233405 modified "2023-10-11" @default.
• W2053233405 title "Genomewide Linkage Scan for Diabetic Renal Failure and Albuminuria: The FIND Study" @default.
• W2053233405 cites W1976525846 @default.
• W2053233405 cites W1991595901 @default.
• W2053233405 cites W2013935385 @default.
• W2053233405 cites W2017376747 @default.
• W2053233405 cites W2034459587 @default.
• W2053233405 cites W2048740425 @default.
• W2053233405 cites W2054754144 @default.
• W2053233405 cites W2057292957 @default.
• W2053233405 cites W2058286579 @default.
• W2053233405 cites W2083728668 @default.
• W2053233405 cites W2100675461 @default.
• W2053233405 cites W2105840050 @default.
• W2053233405 cites W2108262582 @default.
• W2053233405 cites W2111707748 @default.
• W2053233405 cites W2116007807 @default.
• W2053233405 cites W2121965895 @default.
• W2053233405 cites W2124641083 @default.
• W2053233405 cites W2126613720 @default.
• W2053233405 cites W2127935387 @default.
• W2053233405 cites W2131261706 @default.
• W2053233405 cites W2143844210 @default.
• W2053233405 cites W2157802706 @default.
• W2053233405 cites W2160180886 @default.
• W2053233405 cites W2161840616 @default.
• W2053233405 cites W2169915264 @default.
• W2053233405 cites W4239914585 @default.
• W2053233405 cites W4249227027 @default.
• W2053233405 doi "https://doi.org/10.1159/000326763" @default.
• W2053233405 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3078269" @default.
• W2053233405 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21454968" @default.
• W2053233405 hasPublicationYear "2011" @default.
• W2053233405 type Work @default.
• W2053233405 sameAs 2053233405 @default.
• W2053233405 citedByCount "53" @default.
• W2053233405 countsByYear W20532334052012 @default.
• W2053233405 countsByYear W20532334052013 @default.
• W2053233405 countsByYear W20532334052014 @default.
• W2053233405 countsByYear W20532334052015 @default.
• W2053233405 countsByYear W20532334052016 @default.
• W2053233405 countsByYear W20532334052017 @default.
• W2053233405 countsByYear W20532334052018 @default.
• W2053233405 countsByYear W20532334052019 @default.
• W2053233405 countsByYear W20532334052020 @default.
• W2053233405 countsByYear W20532334052021 @default.
• W2053233405 countsByYear W20532334052023 @default.
• W2053233405 crossrefType "journal-article" @default.
• W2053233405 hasAuthorship W2053233405A5002770996 @default.
• W2053233405 hasAuthorship W2053233405A5004754655 @default.
• W2053233405 hasAuthorship W2053233405A5005079192 @default.
• W2053233405 hasAuthorship W2053233405A5008471831 @default.
• W2053233405 hasAuthorship W2053233405A5009102261 @default.
• W2053233405 hasAuthorship W2053233405A5017342914 @default.
• W2053233405 hasAuthorship W2053233405A5017453385 @default.
• W2053233405 hasAuthorship W2053233405A5024733766 @default.
• W2053233405 hasAuthorship W2053233405A5030650722 @default.
• W2053233405 hasAuthorship W2053233405A5031109876 @default.
• W2053233405 hasAuthorship W2053233405A5034748018 @default.
• W2053233405 hasAuthorship W2053233405A5037848101 @default.
• W2053233405 hasAuthorship W2053233405A5041935551 @default.
• W2053233405 hasAuthorship W2053233405A5042371019 @default.
• W2053233405 hasAuthorship W2053233405A5049047999 @default.

• next