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- W2053238051 abstract "Hepatitis C virus (HCV) infection is common in transfusion-dependent thalassaemia. The clinical usefulness of 12-month treatment, using interferon alpha 3 MIU/m2 thrice weekly and oral ribavirin 16 mg/kg/d, was evaluated in 18 previously untreated thalassaemia patients. The median age at start of treatment was 16 years (range 7-29). Fourteen were infected with genotype 1b and 4 with genotype 6a. The sustained biochemical and virological response rates 6 months after stopping treatment were both 72.2%. Blood consumption was temporarily increased by 30% due to ribavirin-associated haemolysis. This study demonstrated a high, sustained response rate to combination treatment despite infection with genotype 1b." @default.
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- W2053238051 date "2002-05-19" @default.
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- W2053238051 title "Interferon and ribavirin as frontline treatment for chronic hepatitis C infection in thalassaemia major" @default.
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- W2053238051 doi "https://doi.org/10.1046/j.1365-2141.2002.03491.x" @default.
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