Matches in SemOpenAlex for { <https://semopenalex.org/work/W2053241796> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2053241796 endingPage "377" @default.
- W2053241796 startingPage "372" @default.
- W2053241796 abstract "To assess whether the quantitative and qualitative aspects of cortisol, 17-hydroxyprogesterone (17-OHP), and androstenedi-one (D4A) secretion in patients with nonclassic congenital adrenal hyperplasia (NCCAH) differ from those in normal children, 24-hour serum concentrations of these steroids were measured in five prepubertal patients with NCCAH and five normal prepubertal children. Adrenal steroid profiles obtained by 30-minute sampling were analyzed by the Pulsar program. In comparison to normal children, the 24-hour quantitative parameters of 17-OHP and D4A secretion were significantly greater in NCCAH patients, but serum cortisol concentrations were similar in the two groups. When daytime and nighttime hormone releases were separately analyzed, a significant nocturnal elevation of the cortisol area under the curve above zero level (AUCo) and 12-hour mean and 17-OHP AUCo, AUC above baseline, mean peak height, amplitude, area, and 12-hour mean was detected in normal subjects only. Conversely, NCCAH patients exhibited an increased frequency and number of 17-OHP secretory peaks at night together with a reduction of the interpeak interval. No significant day/night differences in D4A concentrations were detected either in normals or in the patients. In conclusion, the results of the present study indicate that patients with NCCAH have a distinct pattern of adrenal steroid secretion characterized by a high-frequency 17-OHP release accompanied by a relative nocturnal cortisol deficiency." @default.
- W2053241796 created "2016-06-24" @default.
- W2053241796 creator A5015242920 @default.
- W2053241796 creator A5021561960 @default.
- W2053241796 creator A5031815056 @default.
- W2053241796 creator A5032895719 @default.
- W2053241796 creator A5038156868 @default.
- W2053241796 creator A5070978913 @default.
- W2053241796 creator A5075683382 @default.
- W2053241796 creator A5081276442 @default.
- W2053241796 date "1994-03-01" @default.
- W2053241796 modified "2023-09-27" @default.
- W2053241796 title "Dynamics of 24-hour pulsatile cortisol, 17-hydroxyprogesterone, and androstenedione release in prepubertal patients with nonclassic 21-hydroxylase deficiency and normal prepubertal children" @default.
- W2053241796 cites W1977831476 @default.
- W2053241796 cites W2041214980 @default.
- W2053241796 cites W2066590152 @default.
- W2053241796 cites W2082409955 @default.
- W2053241796 cites W2085685544 @default.
- W2053241796 cites W2093801820 @default.
- W2053241796 cites W2094741615 @default.
- W2053241796 cites W2145641065 @default.
- W2053241796 cites W2156604382 @default.
- W2053241796 cites W2161209070 @default.
- W2053241796 doi "https://doi.org/10.1016/0026-0495(94)90107-4" @default.
- W2053241796 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8139487" @default.
- W2053241796 hasPublicationYear "1994" @default.
- W2053241796 type Work @default.
- W2053241796 sameAs 2053241796 @default.
- W2053241796 citedByCount "19" @default.
- W2053241796 countsByYear W20532417962016 @default.
- W2053241796 countsByYear W20532417962020 @default.
- W2053241796 countsByYear W20532417962021 @default.
- W2053241796 crossrefType "journal-article" @default.
- W2053241796 hasAuthorship W2053241796A5015242920 @default.
- W2053241796 hasAuthorship W2053241796A5021561960 @default.
- W2053241796 hasAuthorship W2053241796A5031815056 @default.
- W2053241796 hasAuthorship W2053241796A5032895719 @default.
- W2053241796 hasAuthorship W2053241796A5038156868 @default.
- W2053241796 hasAuthorship W2053241796A5070978913 @default.
- W2053241796 hasAuthorship W2053241796A5075683382 @default.
- W2053241796 hasAuthorship W2053241796A5081276442 @default.
- W2053241796 hasConcept C126322002 @default.
- W2053241796 hasConcept C134018914 @default.
- W2053241796 hasConcept C2776683971 @default.
- W2053241796 hasConcept C2777334680 @default.
- W2053241796 hasConcept C2777767042 @default.
- W2053241796 hasConcept C2777911890 @default.
- W2053241796 hasConcept C2778709874 @default.
- W2053241796 hasConcept C2780321258 @default.
- W2053241796 hasConcept C2988731192 @default.
- W2053241796 hasConcept C71315377 @default.
- W2053241796 hasConcept C71924100 @default.
- W2053241796 hasConcept C76318530 @default.
- W2053241796 hasConceptScore W2053241796C126322002 @default.
- W2053241796 hasConceptScore W2053241796C134018914 @default.
- W2053241796 hasConceptScore W2053241796C2776683971 @default.
- W2053241796 hasConceptScore W2053241796C2777334680 @default.
- W2053241796 hasConceptScore W2053241796C2777767042 @default.
- W2053241796 hasConceptScore W2053241796C2777911890 @default.
- W2053241796 hasConceptScore W2053241796C2778709874 @default.
- W2053241796 hasConceptScore W2053241796C2780321258 @default.
- W2053241796 hasConceptScore W2053241796C2988731192 @default.
- W2053241796 hasConceptScore W2053241796C71315377 @default.
- W2053241796 hasConceptScore W2053241796C71924100 @default.
- W2053241796 hasConceptScore W2053241796C76318530 @default.
- W2053241796 hasIssue "3" @default.
- W2053241796 hasLocation W20532417961 @default.
- W2053241796 hasLocation W20532417962 @default.
- W2053241796 hasOpenAccess W2053241796 @default.
- W2053241796 hasPrimaryLocation W20532417961 @default.
- W2053241796 hasRelatedWork W1982490216 @default.
- W2053241796 hasRelatedWork W2053241796 @default.
- W2053241796 hasRelatedWork W2056192651 @default.
- W2053241796 hasRelatedWork W2057595342 @default.
- W2053241796 hasRelatedWork W2060998559 @default.
- W2053241796 hasRelatedWork W2063032931 @default.
- W2053241796 hasRelatedWork W2066590152 @default.
- W2053241796 hasRelatedWork W2068072549 @default.
- W2053241796 hasRelatedWork W2136275852 @default.
- W2053241796 hasRelatedWork W2159809643 @default.
- W2053241796 hasVolume "43" @default.
- W2053241796 isParatext "false" @default.
- W2053241796 isRetracted "false" @default.
- W2053241796 magId "2053241796" @default.
- W2053241796 workType "article" @default.