Matches in SemOpenAlex for { <https://semopenalex.org/work/W2053242114> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2053242114 endingPage "7307" @default.
- W2053242114 startingPage "7303" @default.
- W2053242114 abstract "Ribozymes are potentially very powerful agents for perturbing intracellular gene expression. However, pilot experiments in eukaryotes have met with mixed success. We now report that a ribozyme designed to cleave the integrase gene of the human immunodeficiency virus (HIV), when transcribed from a plasmid in Escherichia coli, led to destruction of integrase RNA and complete blockage of integrase protein synthesis. These results indicate that ribozymes can be used to study intracellular gene expression in bacteria and that the HIV-1 integrase gene may be a useful target for therapeutic ribozymes." @default.
- W2053242114 created "2016-06-24" @default.
- W2053242114 creator A5006395020 @default.
- W2053242114 creator A5066266492 @default.
- W2053242114 date "1991-08-15" @default.
- W2053242114 modified "2023-09-23" @default.
- W2053242114 title "Prevention of human immunodeficiency virus type 1 integrase expression in Escherichia coli by a ribozyme." @default.
- W2053242114 cites W1496425492 @default.
- W2053242114 cites W1646843515 @default.
- W2053242114 cites W1659719610 @default.
- W2053242114 cites W1975993749 @default.
- W2053242114 cites W1977335029 @default.
- W2053242114 cites W1986232581 @default.
- W2053242114 cites W2014411093 @default.
- W2053242114 cites W2014568295 @default.
- W2053242114 cites W2017492242 @default.
- W2053242114 cites W2018289835 @default.
- W2053242114 cites W2050599251 @default.
- W2053242114 cites W2050992506 @default.
- W2053242114 cites W2062579188 @default.
- W2053242114 cites W2062911181 @default.
- W2053242114 cites W2065979160 @default.
- W2053242114 cites W2073263035 @default.
- W2053242114 cites W2077077811 @default.
- W2053242114 cites W2078119356 @default.
- W2053242114 cites W2085272777 @default.
- W2053242114 cites W2101108802 @default.
- W2053242114 cites W2134812217 @default.
- W2053242114 cites W2146398256 @default.
- W2053242114 cites W2155703866 @default.
- W2053242114 doi "https://doi.org/10.1073/pnas.88.16.7303" @default.
- W2053242114 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/52283" @default.
- W2053242114 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1871136" @default.
- W2053242114 hasPublicationYear "1991" @default.
- W2053242114 type Work @default.
- W2053242114 sameAs 2053242114 @default.
- W2053242114 citedByCount "108" @default.
- W2053242114 countsByYear W20532421142012 @default.
- W2053242114 crossrefType "journal-article" @default.
- W2053242114 hasAuthorship W2053242114A5006395020 @default.
- W2053242114 hasAuthorship W2053242114A5066266492 @default.
- W2053242114 hasBestOaLocation W20532421142 @default.
- W2053242114 hasConcept C104317684 @default.
- W2053242114 hasConcept C1342335 @default.
- W2053242114 hasConcept C14430832 @default.
- W2053242114 hasConcept C150194340 @default.
- W2053242114 hasConcept C153911025 @default.
- W2053242114 hasConcept C159047783 @default.
- W2053242114 hasConcept C19014433 @default.
- W2053242114 hasConcept C22744801 @default.
- W2053242114 hasConcept C30951146 @default.
- W2053242114 hasConcept C54355233 @default.
- W2053242114 hasConcept C547475151 @default.
- W2053242114 hasConcept C552990157 @default.
- W2053242114 hasConcept C67705224 @default.
- W2053242114 hasConcept C76346623 @default.
- W2053242114 hasConcept C86803240 @default.
- W2053242114 hasConceptScore W2053242114C104317684 @default.
- W2053242114 hasConceptScore W2053242114C1342335 @default.
- W2053242114 hasConceptScore W2053242114C14430832 @default.
- W2053242114 hasConceptScore W2053242114C150194340 @default.
- W2053242114 hasConceptScore W2053242114C153911025 @default.
- W2053242114 hasConceptScore W2053242114C159047783 @default.
- W2053242114 hasConceptScore W2053242114C19014433 @default.
- W2053242114 hasConceptScore W2053242114C22744801 @default.
- W2053242114 hasConceptScore W2053242114C30951146 @default.
- W2053242114 hasConceptScore W2053242114C54355233 @default.
- W2053242114 hasConceptScore W2053242114C547475151 @default.
- W2053242114 hasConceptScore W2053242114C552990157 @default.
- W2053242114 hasConceptScore W2053242114C67705224 @default.
- W2053242114 hasConceptScore W2053242114C76346623 @default.
- W2053242114 hasConceptScore W2053242114C86803240 @default.
- W2053242114 hasIssue "16" @default.
- W2053242114 hasLocation W20532421141 @default.
- W2053242114 hasLocation W20532421142 @default.
- W2053242114 hasLocation W20532421143 @default.
- W2053242114 hasLocation W20532421144 @default.
- W2053242114 hasOpenAccess W2053242114 @default.
- W2053242114 hasPrimaryLocation W20532421141 @default.
- W2053242114 hasRelatedWork W1498473683 @default.
- W2053242114 hasRelatedWork W2001396871 @default.
- W2053242114 hasRelatedWork W2038251099 @default.
- W2053242114 hasRelatedWork W2053242114 @default.
- W2053242114 hasRelatedWork W2064179107 @default.
- W2053242114 hasRelatedWork W2094375788 @default.
- W2053242114 hasRelatedWork W2121088120 @default.
- W2053242114 hasRelatedWork W2357085341 @default.
- W2053242114 hasRelatedWork W2378807662 @default.
- W2053242114 hasRelatedWork W2386840998 @default.
- W2053242114 hasVolume "88" @default.
- W2053242114 isParatext "false" @default.
- W2053242114 isRetracted "false" @default.
- W2053242114 magId "2053242114" @default.
- W2053242114 workType "article" @default.