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- W2053285212 abstract "This study presents the results of in vitro dissolution of controlled-release theophylline tablets using hydroxypropylmethylcellulose as a rate-retarding polymer. The effects of the proportion of the polymer, the addition of diluents, and the surface area of matrix tablets on the theophylline release rate have been investigated. The results of the dissolution tests show that the drug was gradually released in all cases, and that the tablets had released 80% of their contents after 8 hr. The release rate decreased when the proportion of the polymer increased. The influence of adding diluents and effect of the surface area of matrix tablets were not observed in this study." @default.
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- W2053285212 date "1997-01-01" @default.
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- W2053285212 title "Influence of Technological Variables on the Release of Theophylline from Hydrophilic Matrix Tablets" @default.
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- W2053285212 doi "https://doi.org/10.3109/03639049709149818" @default.
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