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- W2053292214 abstract "A myomodulin peptide has been suggested to mediate the response of the giant glial cells to stimulation of the Leydig interneuron in the central nervous system of the leech Hirudo medicinalis [Eur. J. Neurosci. 11 (1999) 3125]. We have now studied the glial response to the endogenous leech MM peptide (GMGALRL-NH2, MMHir). The peptide evokes a membrane outward current (EC50 ∼2 μM), which neither desensitizes nor shows any sign of run-down, and elicits a K+ conductance increase of the glial cell membrane. The peptidase inhibitor phenylmethylsulfonyl fluoride (PMSF) enhances the glial current response, suggesting the presence of endogenous extracellular peptidases." @default.
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- W2053292214 creator A5055061942 @default.
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- W2053292214 date "2002-12-01" @default.
- W2053292214 modified "2023-09-26" @default.
- W2053292214 title "Membrane responses of the leech giant glial cell to the peptide transmitter myomodulin" @default.
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- W2053292214 doi "https://doi.org/10.1016/s0196-9781(02)00255-3" @default.
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