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- W2053294552 abstract "Abstract N-substituted-2-pyridone derivatives have many pharmaceutical properties. In our research, we have developed an efficient, green, and multicomponent protocol to synthesize such new fused N-substituted-2-pyridone derivatives. Optimum reaction condition was obtained by employing l -proline as an organocatalyst in aqueous SDS solution at 100 °C. Various 1,3-diketones, including indane 1,3-dione with a range of aromatic and aliphatic amines were utilized to synthesize fused 2-pyridone derivatives. The isolation of a reaction intermediate confirmed our proposed mechanism. Water as a reaction medium improved the scope of the reaction methodology to a large extent." @default.
- W2053294552 created "2016-06-24" @default.
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- W2053294552 date "2014-09-18" @default.
- W2053294552 modified "2023-09-27" @default.
- W2053294552 title "ChemInform Abstract: L-Proline Catalyzed Expeditious Multicomponent Protocol for the Synthesis of Fused N-Substituted-2-pyridone Derivatives in Aqueous Medium." @default.
- W2053294552 cites W2950338874 @default.
- W2053294552 doi "https://doi.org/10.1002/chin.201440167" @default.
- W2053294552 hasPublicationYear "2014" @default.
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