FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2053345161> ?p ?o ?g. }

• W2053345161 endingPage "93" @default.
• W2053345161 startingPage "88" @default.
• W2053345161 abstract "New triple therapy for eradication of Helicobacter pylori based on a proton pump inhibitor (PPI) provides a cure rate of approximately 90% with few adverse effects. Recently, a PPI-based quadruple therapy, which consists of a PPI plus bismuth-based triple therapy for 7 days, has been studied, and a sufficient eradication rate has been achieved. However, a shorter duration results in improved compliance. In this study, newly developed short-term, simple twice-daily quadruple therapy consisting of rabeprazole, amoxicillin, clarithromycin, and metronidazole (RACM) was compared with a PPI-based triple-therapy regimen for eradication of H. pylori.This study was designed as a randomized open, prospective single-center study. Of a total of 105 H. pylori-positive patients, 55 received the RACM regimen for 5 days (rabeprazole, 10 mg bid; amoxicillin, 750 mg bid; clarithromycin, 200 mg bid; and metronidazole, 250 mg bid), and 50 received the RAC regimen for 5 days (rabeprazole, 10 mg bid; amoxicillin, 750 mg bid; and clarithromycin, 200 mg bid). Cure of the infection was assessed by HpSA (H. pylori stool antigen immunoassay) 1 month after completion of therapy.The rates of eradication of H. pylori by RACM versus RAC were 94.5% (95% CI, 85-99) versus 80.0% (95% CI, 66-90) by intention-to-treat analysis; 98.1% (95% CI, 90-100) versus 87.0% (95% CI, 74-95) by all-patients-treated analysis; and 98.1% (95% CI, 90-100) versus 86.7% (95% CI, 73-95) by per-protocol analysis. No major adverse effects were reported, and 98.0% of patients reported complete compliance.The simple twice-daily and short-term quadruple regimen for only 5 days provided an excellent eradication rate. Compliance with the regimen was high, and serious adverse effects were few. Therefore, the RACM regimen can be considered as safe and effective." @default.
• W2053345161 created "2016-06-24" @default.
• W2053345161 creator A5003135996 @default.
• W2053345161 creator A5022159060 @default.
• W2053345161 creator A5036590154 @default.
• W2053345161 creator A5049109349 @default.
• W2053345161 creator A5054057203 @default.
• W2053345161 creator A5057705404 @default.
• W2053345161 creator A5082746028 @default.
• W2053345161 date "2000-06-01" @default.
• W2053345161 modified "2023-09-23" @default.
• W2053345161 title "Addition of Metronidazole to Rabeprazole-Amoxicillin-Clarithromycin Regimen for Helicobacter pylori Infection Provides an Excellent Cure Rate with Five-Day Therapy" @default.
• W2053345161 cites W1544042744 @default.
• W2053345161 cites W1971649753 @default.
• W2053345161 cites W1976854776 @default.
• W2053345161 cites W1976931158 @default.
• W2053345161 cites W1985761582 @default.
• W2053345161 cites W1986924432 @default.
• W2053345161 cites W1987243831 @default.
• W2053345161 cites W1993415966 @default.
• W2053345161 cites W1994405603 @default.
• W2053345161 cites W2002526633 @default.
• W2053345161 cites W2011021437 @default.
• W2053345161 cites W2030920817 @default.
• W2053345161 cites W2053130872 @default.
• W2053345161 cites W2057863812 @default.
• W2053345161 cites W2058740076 @default.
• W2053345161 cites W2105128699 @default.
• W2053345161 cites W2106298592 @default.
• W2053345161 cites W2123808302 @default.
• W2053345161 cites W2123848597 @default.
• W2053345161 cites W2136901066 @default.
• W2053345161 cites W2141274436 @default.
• W2053345161 cites W2152333625 @default.
• W2053345161 doi "https://doi.org/10.1046/j.1523-5378.2000.00013.x" @default.
• W2053345161 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10849057" @default.
• W2053345161 hasPublicationYear "2000" @default.
• W2053345161 type Work @default.
• W2053345161 sameAs 2053345161 @default.
• W2053345161 citedByCount "61" @default.
• W2053345161 countsByYear W20533451612012 @default.
• W2053345161 countsByYear W20533451612013 @default.
• W2053345161 countsByYear W20533451612014 @default.
• W2053345161 countsByYear W20533451612015 @default.
• W2053345161 countsByYear W20533451612016 @default.
• W2053345161 countsByYear W20533451612017 @default.
• W2053345161 countsByYear W20533451612018 @default.
• W2053345161 countsByYear W20533451612020 @default.
• W2053345161 countsByYear W20533451612023 @default.
• W2053345161 crossrefType "journal-article" @default.
• W2053345161 hasAuthorship W2053345161A5003135996 @default.
• W2053345161 hasAuthorship W2053345161A5022159060 @default.
• W2053345161 hasAuthorship W2053345161A5036590154 @default.
• W2053345161 hasAuthorship W2053345161A5049109349 @default.
• W2053345161 hasAuthorship W2053345161A5054057203 @default.
• W2053345161 hasAuthorship W2053345161A5057705404 @default.
• W2053345161 hasAuthorship W2053345161A5082746028 @default.
• W2053345161 hasConcept C126322002 @default.
• W2053345161 hasConcept C197934379 @default.
• W2053345161 hasConcept C2776409635 @default.
• W2053345161 hasConcept C2776962512 @default.
• W2053345161 hasConcept C2777396551 @default.
• W2053345161 hasConcept C2779116819 @default.
• W2053345161 hasConcept C2779708577 @default.
• W2053345161 hasConcept C2781025758 @default.
• W2053345161 hasConcept C2781413609 @default.
• W2053345161 hasConcept C501593827 @default.
• W2053345161 hasConcept C71924100 @default.
• W2053345161 hasConcept C86803240 @default.
• W2053345161 hasConcept C89423630 @default.
• W2053345161 hasConcept C90924648 @default.
• W2053345161 hasConceptScore W2053345161C126322002 @default.
• W2053345161 hasConceptScore W2053345161C197934379 @default.
• W2053345161 hasConceptScore W2053345161C2776409635 @default.
• W2053345161 hasConceptScore W2053345161C2776962512 @default.
• W2053345161 hasConceptScore W2053345161C2777396551 @default.
• W2053345161 hasConceptScore W2053345161C2779116819 @default.
• W2053345161 hasConceptScore W2053345161C2779708577 @default.
• W2053345161 hasConceptScore W2053345161C2781025758 @default.
• W2053345161 hasConceptScore W2053345161C2781413609 @default.
• W2053345161 hasConceptScore W2053345161C501593827 @default.
• W2053345161 hasConceptScore W2053345161C71924100 @default.
• W2053345161 hasConceptScore W2053345161C86803240 @default.
• W2053345161 hasConceptScore W2053345161C89423630 @default.
• W2053345161 hasConceptScore W2053345161C90924648 @default.
• W2053345161 hasIssue "2" @default.
• W2053345161 hasLocation W20533451611 @default.
• W2053345161 hasLocation W20533451612 @default.
• W2053345161 hasOpenAccess W2053345161 @default.
• W2053345161 hasPrimaryLocation W20533451611 @default.
• W2053345161 hasRelatedWork W1979182627 @default.
• W2053345161 hasRelatedWork W2025995260 @default.
• W2053345161 hasRelatedWork W2036432661 @default.
• W2053345161 hasRelatedWork W2042275550 @default.
• W2053345161 hasRelatedWork W2048052622 @default.
• W2053345161 hasRelatedWork W2063246590 @default.
• W2053345161 hasRelatedWork W2092087978 @default.
• W2053345161 hasRelatedWork W2116916903 @default.

• next