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• W2053395087 abstract "The effects of dietary zinc (Zn) and cadmium (Cd) on tissue selenium (Se) concentration and glutathione peroxidase (GSH-Px) activity were studied in weanling male Wistar rats. One group of rats was fed a purified diet based on casein and sucrose, and the other rats used in a 2×2×2 factorial arrangement of treatment were fed this diet supplemented with 0.1mg Se/kg, either as DL-selenomethionine or sodium selenite and plus 100mg Zn/kg as zinc sulfate or 5mg Cd/kg as cadmium chloride or both for 4 weeks. Se concentrations in plasma, erythrocytes, muscle, heart, and liver were significantly elevated by Zn. Cd significantly decreased Se concentration in muscle. Addition of Zn to the diets markedly increased (p<0.001) hepatic GSH-Px activity. However, Cd in the diets produced a significant increase (p<0.001) in erythrocyte GSH-Px activity. These results indicate that Zn level of marginal deficiency(8.6mg/kg diet) can decrease Se availability and a small excess of Zn increases Se availability for hepatic GSH-Px activity." @default.
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• W2053395087 date "1991-01-01" @default.
• W2053395087 modified "2023-10-16" @default.
• W2053395087 title "Effects of dietary zinc and cadmium on tissue selenium concentration and glutathione peroxidase activity in rats fed DL-selenomethionine or sodium selenite." @default.
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• W2053395087 doi "https://doi.org/10.3177/jnsv.37.29" @default.
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