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• W2053418438 endingPage "1066" @default.
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• W2053418438 abstract "In 1995, changes in our hospital formulary were made to limit an outbreak of vancomycin-resistant enterococci and resulted in decreased usage of cephalosporins, imipenem, clindamycin, and vancomycin and increased usage of beta-lactam/beta-lactamase-inhibitor antibiotics. In this report, the effect of this formulary change on other resistant pathogens is described. Following the formulary change, there was a reduction in the monthly number (mean +/- SD) of patients with methicillin-resistant Staphylococcus aureus (from 21.9 +/- 8.1 to 17.2 +/- 7.2 patients/1,000 discharges; P = .03) and ceftazidime-resistant Klebsiella pneumoniae (from 8.6 +/- 4.3 to 5.7 +/- 4.0 patients/1,000 discharges; P = .02). However, there was an increase in the number of patients with cultures positive for cefotaxime-resistant Acinetobacter species (from 2.4 +/- 2.2 to 5.4 +/- 4.0 patients/1,000 discharges; P = .02). Altering an antibiotic formulary may be a possible mechanism to contain the spread of selected resistant pathogens. However, close surveillance is needed to detect the emergence of other resistant pathogens." @default.
• W2053418438 created "2016-06-24" @default.
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• W2053418438 date "1999-05-01" @default.
• W2053418438 modified "2023-10-02" @default.
• W2053418438 title "Reduction in the Incidence of Methicillin‐Resistant Staphylococcus aureus and Ceftazidime‐Resistant Klebsiella pneumoniae Following Changes in a Hospital Antibiotic Formulary" @default.
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• W2053418438 doi "https://doi.org/10.1086/514743" @default.
• W2053418438 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10452635" @default.
• W2053418438 hasPublicationYear "1999" @default.
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