Matches in SemOpenAlex for { <https://semopenalex.org/work/W2053442911> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2053442911 endingPage "312" @default.
- W2053442911 startingPage "307" @default.
- W2053442911 abstract "Fast kinetics of transient pH changes and difference spectrum formation have been investigated following mixing of ADP/ATP with partially purified plasma membrane PM‐ATPase of the pathogenic yeast Candida albicans in the presence of five nutrients: glucose, glutamic acid, proline, lysine, and arginine and two analogs of glucose: 2‐deoxy D‐glucose and xylose. Average hT‐absorption to release ratio, indicative of population of ATPase undergoing complete hydrolytic cycle, was found to be 0.27 for control. This ratio varied between 0.25 (proline) to 0.36 (arginine) for all other compounds tested, except for glucose. In the presence of glucose, H+‐absorption to release ratio was exceptionally high (0.92). While no UV difference spectrum was observed with ADP, mixing of ATP with ATPase led to a large conformationai change. Exposure to different nutrients restricted the magnitude of the conformationai change; the analogs of glucose were found to be ineffective. This suppression was maximal in the case of glucose (80%); with other nutrients, the magnitude of suppression ranged from 40–50%. Rate of H+‐absorption, which is indicative of E∼P complex dissociation, showed positive correlation with suppression of conformationai change only in the case of glucose and no other nutrient/analog. Mode of interaction of glucose with plasma membrane H+‐ATPase thus appears to be strikingly distinct compared to that of other nutrients/analogs tested. The results obtained lead us to propose a model for explaining glucose stimulation of plasma membrane H+‐ATPase activity." @default.
- W2053442911 created "2016-06-24" @default.
- W2053442911 creator A5020663404 @default.
- W2053442911 creator A5072339263 @default.
- W2053442911 creator A5081169465 @default.
- W2053442911 creator A5082663725 @default.
- W2053442911 date "2004-01-01" @default.
- W2053442911 modified "2023-09-27" @default.
- W2053442911 title "Effect of glucose, its analogs and some amino acids on pre‐steady state kinetics of ATP hydrolysis by PM‐ATPase ofpathogenic yeast(candida albicans)" @default.
- W2053442911 cites W1664022161 @default.
- W2053442911 cites W1968870996 @default.
- W2053442911 cites W1973691380 @default.
- W2053442911 cites W1976145314 @default.
- W2053442911 cites W2001683463 @default.
- W2053442911 cites W2010441562 @default.
- W2053442911 cites W2030228405 @default.
- W2053442911 cites W2036873028 @default.
- W2053442911 cites W2039858152 @default.
- W2053442911 cites W2051795565 @default.
- W2053442911 cites W2077740252 @default.
- W2053442911 cites W2092235258 @default.
- W2053442911 doi "https://doi.org/10.1080/12265071.2004.9647765" @default.
- W2053442911 hasPublicationYear "2004" @default.
- W2053442911 type Work @default.
- W2053442911 sameAs 2053442911 @default.
- W2053442911 citedByCount "15" @default.
- W2053442911 countsByYear W20534429112012 @default.
- W2053442911 countsByYear W20534429112013 @default.
- W2053442911 countsByYear W20534429112015 @default.
- W2053442911 crossrefType "journal-article" @default.
- W2053442911 hasAuthorship W2053442911A5020663404 @default.
- W2053442911 hasAuthorship W2053442911A5072339263 @default.
- W2053442911 hasAuthorship W2053442911A5081169465 @default.
- W2053442911 hasAuthorship W2053442911A5082663725 @default.
- W2053442911 hasBestOaLocation W20534429111 @default.
- W2053442911 hasConcept C134018914 @default.
- W2053442911 hasConcept C141315368 @default.
- W2053442911 hasConcept C161573976 @default.
- W2053442911 hasConcept C181199279 @default.
- W2053442911 hasConcept C185592680 @default.
- W2053442911 hasConcept C23265538 @default.
- W2053442911 hasConcept C2777468819 @default.
- W2053442911 hasConcept C2779306644 @default.
- W2053442911 hasConcept C2779815552 @default.
- W2053442911 hasConcept C2780917455 @default.
- W2053442911 hasConcept C515207424 @default.
- W2053442911 hasConcept C55493867 @default.
- W2053442911 hasConcept C86803240 @default.
- W2053442911 hasConcept C89423630 @default.
- W2053442911 hasConceptScore W2053442911C134018914 @default.
- W2053442911 hasConceptScore W2053442911C141315368 @default.
- W2053442911 hasConceptScore W2053442911C161573976 @default.
- W2053442911 hasConceptScore W2053442911C181199279 @default.
- W2053442911 hasConceptScore W2053442911C185592680 @default.
- W2053442911 hasConceptScore W2053442911C23265538 @default.
- W2053442911 hasConceptScore W2053442911C2777468819 @default.
- W2053442911 hasConceptScore W2053442911C2779306644 @default.
- W2053442911 hasConceptScore W2053442911C2779815552 @default.
- W2053442911 hasConceptScore W2053442911C2780917455 @default.
- W2053442911 hasConceptScore W2053442911C515207424 @default.
- W2053442911 hasConceptScore W2053442911C55493867 @default.
- W2053442911 hasConceptScore W2053442911C86803240 @default.
- W2053442911 hasConceptScore W2053442911C89423630 @default.
- W2053442911 hasIssue "4" @default.
- W2053442911 hasLocation W20534429111 @default.
- W2053442911 hasOpenAccess W2053442911 @default.
- W2053442911 hasPrimaryLocation W20534429111 @default.
- W2053442911 hasRelatedWork W157413440 @default.
- W2053442911 hasRelatedWork W1953512387 @default.
- W2053442911 hasRelatedWork W1971690527 @default.
- W2053442911 hasRelatedWork W1990466210 @default.
- W2053442911 hasRelatedWork W2053442911 @default.
- W2053442911 hasRelatedWork W2086449260 @default.
- W2053442911 hasRelatedWork W2090911004 @default.
- W2053442911 hasRelatedWork W2104029270 @default.
- W2053442911 hasRelatedWork W2180148536 @default.
- W2053442911 hasRelatedWork W4245074755 @default.
- W2053442911 hasVolume "8" @default.
- W2053442911 isParatext "false" @default.
- W2053442911 isRetracted "false" @default.
- W2053442911 magId "2053442911" @default.
- W2053442911 workType "article" @default.