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- W2053444552 endingPage "470" @default.
- W2053444552 startingPage "457" @default.
- W2053444552 abstract "Homeobox genes represent a family of highly conserved transcription factors originally discovered to regulate organ patterning during development. More recently, several homeobox genes were shown to affect processes in adult tissue, including angiogenesis and wound healing. Whereas a subset of members of the Hox-family of homeobox genes activate growth and migration to promote angiogenesis or wound healing, other Hox genes function to restore or maintain quiescent, differentiated tissue function. Pathological tissue remodeling is linked to differential expression of activating or stabilizing Hox genes and dysregulation of Hox expression can contribute to disease progression. Studies aimed at understanding the role and regulation of Hox genes have provided insight into how these potent morphoregulatory genes can be applied to enhance tissue engineering or limit cancer progression." @default.
- W2053444552 created "2016-06-24" @default.
- W2053444552 creator A5013668796 @default.
- W2053444552 creator A5073978041 @default.
- W2053444552 creator A5075294396 @default.
- W2053444552 date "2012-11-17" @default.
- W2053444552 modified "2023-10-14" @default.
- W2053444552 title "The dual roles of homeobox genes in vascularization and wound healing" @default.
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