FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2053449294> ?p ?o ?g. }

• W2053449294 endingPage "834" @default.
• W2053449294 startingPage "822" @default.
• W2053449294 abstract "The relation between single skinned skeletal fiber contractile mechanics and the myosin mechanoenzyme was examined by perturbing the actomyosin interaction with the ATP analog CTP in fibers from both rabbit psoas and rat soleus. Tension, instantaneous stiffness, and the rate of tension redevelopment (ktr), under software-based sarcomere length control, were examined at 15 degrees C for a range of Ca2+ concentrations in both fiber types. CTP produced 94% of the maximum ATP-generated tension in psoas fibers and 77% in soleus fibers. In psoas, CTP also increased stiffness to 106% of the ATP stiffness, whereas in soleus stiffness decreased to 92%. Thus, part of the greater difference between maximum ATP- and CTP-generated tension in soleus fibers appears to be due to a decrease in strongly bound cross-bridge number. Interestingly, although the nucleotide exchange produced substantial increases in the steepness (nH) of the tension- and stiffness-pCa relationships in soleus fibers, only minor changes were seen in psoas fibers. At maximum Ca2+ and nominal P(i) levels, ktr in psoas fibers increased from 11.7 s-1 with ATP to 16.6 s-1 with CTP and in soleus fibers from 4.9 to 8.4 s-1. Increased P(i) levels decreased the maximum Ca(2+)-activated tension in both fiber types and increased the ktr of psoas fibers, but the ktr of soleus fibers was not significantly altered. Thus, although the nucleotide exchange generally produced similar changes in the mechanics, there were significant muscle lineage differences in the tension- and stiffness-pCa relations and in the effects of P(i) on ktr, such that differences in contractile mechanics were lessened in the presence of CTP." @default.
• W2053449294 created "2016-06-24" @default.
• W2053449294 creator A5035642806 @default.
• W2053449294 creator A5054849937 @default.
• W2053449294 creator A5085045889 @default.
• W2053449294 date "1997-02-01" @default.
• W2053449294 modified "2023-10-15" @default.
• W2053449294 title "Nucleotide-Dependent Contractile Properties of Ca2+-Activated Fast and Slow Skeletal Muscle Fibers" @default.
• W2053449294 cites W1156084614 @default.
• W2053449294 cites W1499122117 @default.
• W2053449294 cites W1546003942 @default.
• W2053449294 cites W1582432526 @default.
• W2053449294 cites W1678204546 @default.
• W2053449294 cites W1771187790 @default.
• W2053449294 cites W1964192048 @default.
• W2053449294 cites W1966430199 @default.
• W2053449294 cites W1972357724 @default.
• W2053449294 cites W1973756520 @default.
• W2053449294 cites W1979123151 @default.
• W2053449294 cites W1989255509 @default.
• W2053449294 cites W1992443905 @default.
• W2053449294 cites W1992924616 @default.
• W2053449294 cites W2004671192 @default.
• W2053449294 cites W2006420152 @default.
• W2053449294 cites W2025627402 @default.
• W2053449294 cites W2028682257 @default.
• W2053449294 cites W2030547704 @default.
• W2053449294 cites W2036348209 @default.
• W2053449294 cites W2040049613 @default.
• W2053449294 cites W2044175419 @default.
• W2053449294 cites W2045024410 @default.
• W2053449294 cites W2046003039 @default.
• W2053449294 cites W2047644811 @default.
• W2053449294 cites W2070037836 @default.
• W2053449294 cites W2076559561 @default.
• W2053449294 cites W2082594221 @default.
• W2053449294 cites W2083492593 @default.
• W2053449294 cites W2084822214 @default.
• W2053449294 cites W2085261165 @default.
• W2053449294 cites W2088988321 @default.
• W2053449294 cites W2092245262 @default.
• W2053449294 cites W2093741736 @default.
• W2053449294 cites W2104465251 @default.
• W2053449294 cites W2127917887 @default.
• W2053449294 cites W2131931577 @default.
• W2053449294 cites W2132912862 @default.
• W2053449294 cites W2137128469 @default.
• W2053449294 cites W2140994672 @default.
• W2053449294 cites W2150924142 @default.
• W2053449294 cites W2153526297 @default.
• W2053449294 cites W2157503382 @default.
• W2053449294 cites W2161375436 @default.
• W2053449294 cites W2161811610 @default.
• W2053449294 cites W2164856821 @default.
• W2053449294 cites W2271670283 @default.
• W2053449294 cites W2317910597 @default.
• W2053449294 cites W82700264 @default.
• W2053449294 doi "https://doi.org/10.1016/s0006-3495(97)78716-2" @default.
• W2053449294 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1185605" @default.
• W2053449294 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9017207" @default.
• W2053449294 hasPublicationYear "1997" @default.
• W2053449294 type Work @default.
• W2053449294 sameAs 2053449294 @default.
• W2053449294 citedByCount "23" @default.
• W2053449294 countsByYear W20534492942012 @default.
• W2053449294 countsByYear W20534492942013 @default.
• W2053449294 countsByYear W20534492942015 @default.
• W2053449294 countsByYear W20534492942016 @default.
• W2053449294 countsByYear W20534492942017 @default.
• W2053449294 countsByYear W20534492942018 @default.
• W2053449294 countsByYear W20534492942019 @default.
• W2053449294 countsByYear W20534492942020 @default.
• W2053449294 countsByYear W20534492942022 @default.
• W2053449294 crossrefType "journal-article" @default.
• W2053449294 hasAuthorship W2053449294A5035642806 @default.
• W2053449294 hasAuthorship W2053449294A5054849937 @default.
• W2053449294 hasAuthorship W2053449294A5085045889 @default.
• W2053449294 hasBestOaLocation W20534492941 @default.
• W2053449294 hasConcept C104317684 @default.
• W2053449294 hasConcept C105702510 @default.
• W2053449294 hasConcept C112950240 @default.
• W2053449294 hasConcept C12554922 @default.
• W2053449294 hasConcept C134018914 @default.
• W2053449294 hasConcept C159985019 @default.
• W2053449294 hasConcept C178790620 @default.
• W2053449294 hasConcept C185592680 @default.
• W2053449294 hasConcept C186068551 @default.
• W2053449294 hasConcept C191897082 @default.
• W2053449294 hasConcept C192562407 @default.
• W2053449294 hasConcept C207200792 @default.
• W2053449294 hasConcept C2776104385 @default.
• W2053449294 hasConcept C2776329151 @default.
• W2053449294 hasConcept C2779372316 @default.
• W2053449294 hasConcept C2779959927 @default.
• W2053449294 hasConcept C512185932 @default.
• W2053449294 hasConcept C519885992 @default.
• W2053449294 hasConcept C55493867 @default.
• W2053449294 hasConcept C68731436 @default.

• next